Concepedia

Dose-dependent Cardiotoxicity

Dose-Dependent Cardiotoxicity is a form of drug-induced cardiac injury characterized by a progressive increase in the risk and severity of myocardial damage in direct relation to the cumulative administered dose of anthracycline chemotherapy agents.

1.2K

Publications

71.2K

Citations

6.1K

Authors

1.5K

Institutions

Publications per year

2017–2026

309

Parents

Publications

1.2K

Congestive heart failure in patients treated with doxorubicin

Sandra M. Swain, Fredrick S. Whaley, Michael S. Ewer · Cancer · 2003 · 2.3K citations · Full text

, , +15

Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer

E O’Brien, Nely Wigler, Moshe Inbar et al. · Annals of Oncology · 2004 · 1.7K citations · Full text

, , +17

Cardiotoxicity of the cancer therapeutic agent imatinib mesylate

Risto Kerkelä, Luanda Grazette, Rinat Yacobi et al. · Nature Medicine · 2006 · 1.2K citations

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Cardiovascular toxicity induced by chemotherapy, targeted agents and radiotherapy: ESMO Clinical Practice Guidelines

Giuseppe Curigliano, Daniela Cardinale, Thomas Suter et al. · Annals of Oncology · 2012 · 864 citations · Full text

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Female Sex and Higher Drug Dose as Risk Factors for Late Cardiotoxic Effects of Doxorubicin Therapy for Childhood Cancer

Steven E. Lipshultz, Stuart R. Lipsitz, Suzanne M. Mone et al. · New England Journal of Medicine · 1995 · 810 citations · Full text

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Authors

6.1K

  1. GM
    Giorgio Minotti

    Università Campus Bio-Medico, Italy

    14 publications · 833 citations

    13

    h-index

  2. AB
    Aalt Bast

    Maastricht University, Netherlands

    12 publications · 429 citations

    12

    h-index

  3. EH
    Eugene H. Herman

    United States Food and Drug Administration, United States

    11 publications · 601 citations

    11

    h-index

  4. MD
    Maria de Lourdes Bastos

    Universidade do Porto, Portugal

    11 publications · 380 citations

    11

    h-index

  5. VM
    Vera Marisa Costa

    Universidade do Porto, Portugal

    10 publications · 303 citations

    11

    h-index

1–5 of 6.1K

Institutions

1.5K

  1. National Institutes of Health

    Bethesda, United States

    16 h-index

    48 publications

    5.7K citations

  2. United States Food and Drug Administration

    Silver Spring, United States

    15 h-index

    59 publications

    2K citations

  3. Harvard University

    Cambridge, United States

    15 h-index

    42 publications

    11.4K citations

  4. Charles University

    Prague, Czechia

    15 h-index

    93 publications

    2.8K citations

  5. The University of Texas MD Anderson Cancer Center

    Houston, United States

    14 h-index

    56 publications

    9.5K citations

  6. Center for Drug Evaluation and Research

    Silver Spring, United States

    13 h-index

    41 publications

    1.5K citations

  7. National Heart Lung and Blood Institute

    Bethesda, United States

    12 h-index

    29 publications

    2.2K citations

  8. Rede de Química e Tecnologia

    Porto, Portugal

    12 h-index

    74 publications

    2.6K citations

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Venues

  1. PubMed

    Repository · 161 publications · 9.3K citations

    55

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  2. Toxicology and Applied Pharmacology

    TAAP · 29 publications · 1.2K citations

    20

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  3. Cancer

    20 publications · 5.3K citations

    19

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  4. Journal of Clinical Oncology

    22 publications · 4.3K citations

    18

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  5. Cancer Chemotherapy and Pharmacology

    19 publications · 605 citations

    17

    h-index

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