Concepedia

Dose Modification Algorithms

Dose Modification Algorithms is a computational method designed to systematically adjust chemotherapeutic drug dosages based on patient-specific clinical and pharmacokinetic parameters to optimize efficacy and minimize toxicity.

47

Publications

1.6K

Citations

339

Authors

168

Institutions

Publications per year

2017–2026

13

Parents

Publications

47

Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data

Rianne MF van Schie, Judith A.M. Wessels, Saskia le Cessie et al. · European Heart Journal · 2011 · 97 citations · Full text

, , +17

High-dose cytarabine dose modification reduces the incidence of neurotoxicity in patients with renal insufficiency.

G. Adair Smith, Lauren E. Damon, Hope S. Rugo et al. · Journal of Clinical Oncology · 1997 · 91 citations

, , +17

Individual Fluorouracil Dose Adjustment in FOLFOX Based on Pharmacokinetic Follow-Up Compared With Conventional Body-Area-Surface Dosing: A Phase II, Proof-of-Concept Study

Olivier Capitain, Andreaa Asevoaia, M. Boisdron‐Celle et al. · Clinical Colorectal Cancer · 2012 · 84 citations

, , +17

DPD-based adaptive dosing of 5-FU in patients with head and neck cancer: impact on treatment efficacy and toxicity

Chen Yang, Joseph Ciccolini, Aurore Blesius et al. · Cancer Chemotherapy and Pharmacology · 2010 · 77 citations

, , +16

Optimizing the dose in cancer patients treated with imatinib, sunitinib and pazopanib

Nienke A. G. Lankheet, Ingrid M.E. Desar, Sasja F. Mulder et al. · British Journal of Clinical Pharmacology · 2017 · 72 citations · Full text

, , +14

1–5 of 47

Authors

339

  1. CM
    Carla M.L. van Herpen

    Radboud University Nijmegen, Netherlands

    2 publications · 84 citations

    2

    h-index

  2. NP
    Nielka P. van Erp

    Radboud University Nijmegen, Netherlands

    2 publications · 84 citations

    2

    h-index

  3. WT
    Winette T.A. van der Graaf

    Radboud University Nijmegen, Netherlands

    2 publications · 84 citations

    2

    h-index

  4. FR
    Frits R. Rosendaal

    Leiden University Medical Center, Netherlands

    2 publications · 111 citations

    2

    h-index

  5. DM
    David M. Burger

    Radboud University Nijmegen, Netherlands

    2 publications · 84 citations

    2

    h-index

1–5 of 339

Institutions

168

  1. Radboud University Nijmegen

    Nijmegen, The Netherlands

    3 h-index

    14 publications

    590 citations

  2. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    8 publications

    294 citations

  3. Leiden University Medical Center

    Leiden, The Netherlands

    3 h-index

    9 publications

    516 citations

  4. Utrecht University

    Utrecht, The Netherlands

    3 h-index

    12 publications

    605 citations

  5. University Hospital of Bern

    Bern, Switzerland

    2 h-index

    3 publications

    87 citations

  6. DDL Diagnostic Laboratory

    Voorburg, Netherlands

    2 h-index

    2 publications

    111 citations

  7. Radboud University Medical Center

    Nijmegen, The Netherlands

    2 h-index

    13 publications

    576 citations

  8. University of Chicago

    Chicago, United States

    2 h-index

    5 publications

    76 citations

1–8 of 168

Venues

  1. Cancer Chemotherapy and Pharmacology

    5 publications · 192 citations

    5

    h-index

  2. British Journal of Clinical Pharmacology

    BJCP · 2 publications · 108 citations

    2

    h-index

  3. Annals of Oncology

    2 publications · 79 citations

    2

    h-index

  4. PLoS ONE

    1 publications · 28 citations

    1

    h-index

  5. Cancer Investigation

    1 publications · 33 citations

    1

    h-index

1–5