Lauren E. Damon

Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia

Catherine C. Smith, Qi Wang, Chen-Shan Chin et al. · Nature · 2012 · 745 citations

Medicine, Genetics, Hematology +13

Crenolanib is a selective type I pan-FLT3 inhibitor

Catherine C. Smith, Elisabeth A. Lasater, Kimberly C. Lin et al. · Proceedings of the National Academy of Sciences · 2014 · 210 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 “Gatekeeper” F691L Mutation with PLX3397

Catherine C. Smith, Chao Zhang, Kimberly C. Lin et al. · Cancer Discovery · 2015 · 203 citations · Full text

Medicine, Medicinal Chemistry, Oncology +13

Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD

Catherine C. Smith, Elisabeth A. Lasater, Xiaotian Zhu et al. · Blood · 2013 · 128 citations · Full text

Life Sciences, Molecular Biology, Oncology +9

Increased CD62e+ Endothelial Microparticle Levels Predict Poor Outcome in Pulmonary Hypertension Patients

Nicolas Amabile, Vivian Y. Chang, Franca S. Angeli et al. · The Journal of Heart and Lung Transplantation · 2009 · 109 citations

Veterinary Medicine, Cell Biology, Physiology +11