Concepedia

Dormant Replication Origin Activation

Dormant Replication Origin Activation is a regulatory mechanism in DNA replication control whereby licensed but normally inactive replication origins are selectively recruited to initiate DNA synthesis under conditions of replication stress to ensure complete genome duplication.

19

Publications

1.9K

Citations

141

Authors

75

Institutions

Publications per year

2017–2026

8

Parents

Publications

19

Dormant origins licensed by excess Mcm2–7 are required for human cells to survive replicative stress

Xin Ge, Dean A. Jackson, J. Julian Blow · Genes & Development · 2007 · 607 citations · Full text

, , +17

Stalled Fork Rescue via Dormant Replication Origins in Unchallenged S Phase Promotes Proper Chromosome Segregation and Tumor Suppression

Tsuyoshi Kawabata, Spencer W. Luebben, Satoru Yamaguchi et al. · Molecular Cell · 2011 · 211 citations · Full text

, , +16

Inhibition of Histone Deacetylase in Cancer Cells Slows Down Replication Forks, Activates Dormant Origins, and Induces DNA Damage

Chiara Conti, Elisabetta Leo, Gabriel S. Eichler et al. · Cancer Research · 2010 · 155 citations · Full text

, , +17

ATR-Mediated Phosphorylation of FANCI Regulates Dormant Origin Firing in Response to Replication Stress

Yu‐Hung Chen, Mathew V. Jones, Yandong Yin et al. · Molecular Cell · 2015 · 154 citations · Full text

, , +16

Activation of dormant origins of DNA replication in budding yeast

Corrado Santocanale, Karuna Sharma, John F.X. Diffley · Genes & Development · 1999 · 140 citations · Full text

, , +16

1–5 of 19

Authors

141

  1. SR
    Sara Rodríguez‐Acebes

    Spanish National Cancer Research Centre, Spain

    3 publications · 141 citations

    3

    h-index

  2. JM
    Juan Méndez

    Spanish National Cancer Research Centre, Spain

    3 publications · 141 citations

    3

    h-index

  3. OG
    Osvaldo Graña‐Castro

    Spanish National Cancer Research Centre, Spain

    2 publications · 32 citations

    2

    h-index

  4. KJ
    Karolina Jodkowska

    Spanish National Cancer Research Centre, Spain

    2 publications · 32 citations

    2

    h-index

  5. TK
    Tsuyoshi Kawabata

    The University of Osaka, Japan

    2 publications · 240 citations

    2

    h-index

1–5 of 141

Institutions

75

  1. Université Toulouse III - Paul Sabatier

    Toulouse, France

    3 h-index

    5 publications

    74 citations

  2. Spanish National Cancer Research Centre

    Madrid, Spain

    3 h-index

    21 publications

    987 citations

  3. Inserm

    Paris, France

    3 h-index

    5 publications

    74 citations

  4. Centre de Recherches en Cancérologie de Toulouse

    Toulouse, France

    3 h-index

    5 publications

    74 citations

  5. IMDEA Food

    Madrid, Spain

    2 h-index

    2 publications

    32 citations

  6. Masonic Cancer Center

    Minneapolis, United States

    2 h-index

    7 publications

    931 citations

  7. Universitat Politècnica de Catalunya

    Barcelona, Spain

    2 h-index

    6 publications

    96 citations

  8. University of Warsaw

    Warsaw, Poland

    2 h-index

    2 publications

    32 citations

1–8 of 75

Venues

  1. Nature Communications

    3 publications · 177 citations

    3

    h-index

  2. Molecular Cell

    2 publications · 365 citations

    2

    h-index

  3. Genes & Development

    2 publications · 747 citations

    2

    h-index

  4. Nucleic Acids Research

    2 publications · 50 citations

    2

    h-index

  5. International Journal of Molecular Sciences

    IJMS · 1 publications · 17 citations

    1

    h-index

1–5