Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors

Fabio Pessina, Fabio Giavazzi, Yandong Yin, +11

Nature Cell Biology

ChromatinTranscriptional RegulationDna Double-strand BreaksNatural SciencesGenetics +9

CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

Hua Zhang, Camilla L. Christensen, Ruben Dries, +45

Cancer Cell

Cancer ImmunosurveillanceMedicineImmunologyTumor ImmunityImmune Checkpoint Inhibitor +5

An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication

Tatiana N. Moiseeva, Yandong Yin, Michael Calderon, +7

Proceedings of the National Academy of Sciences

Unperturbed Dna ReplicationMolecular BiologyCell CycleReplication ForksReceptor Tyrosine Kinase +14

ATR-Mediated Phosphorylation of FANCI Regulates Dormant Origin Firing in Response to Replication Stress

Yu‐Hung Chen, Mathew V. Jones, Yandong Yin, +6

Molecular Cell

Natural SciencesGeneticsGene RegulationMolecular BiologyCellular Regulatory Mechanism +7

Disruption of Ca ²⁺ _i Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2–Deficient Mice

Joon‐Chul Kim, Marta Pérez-Hernández, Francisco Alvarado, +15

Circulation

Kinetics and Dynamics of DNA Hybridization

Yandong Yin, Xin Zhao

Accounts of Chemical Research

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

C. Nemoz, Virginie Ropars, Philippe Frit, +19

Nature Structural & Molecular Biology

Genome InstabilityMolecular BiologyNon-homologous End JoiningMolecular GeneticsChromosomal Rearrangement +2

Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling

Wei Ting C. Lee, Yandong Yin, Michael J. Morten, +8

Nature Communications

Sequence-Independent Self-Assembly of Germ Granule mRNAs into Homotypic Clusters

Tatjana Trcek, Tyler E. Douglas, Markus Grosch, +6

Molecular Cell

GeneticsGerm Granule MrnasRna Structure PredictionGene StructureMedicine +2

Dynamics of spontaneous flipping of a mismatched base in DNA duplex

Yandong Yin, Lijiang Yang, Guanqun Zheng, +5

Proceedings of the National Academy of Sciences