Concepedia

Dna Hydroxymethylation

DNA Hydroxymethylation is a post-replicative epigenetic modification of DNA in which a hydroxymethyl group is enzymatically added to the fifth carbon of cytosine, distinguishing it from canonical DNA methylation by its role in active demethylation and gene regulation dynamics.

593

Publications

56.5K

Citations

3.6K

Authors

1K

Institutions

Publications per year

2017–2026

244

Variants

5-Hydroxymethylcytosine Modification5Hmc Modification

Parents

Publications

593

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

Yufei He, Bin-Zhong Li, Zheng Li et al. · Science · 2011 · 2.8K citations

, , +12

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

Skirmantas Kriaučionis, Nathaniel Heintz · Science · 2009 · 2.7K citations

, , +15

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

Altuna Akalin, Matthías Kormáksson, Sheng Li et al. · Genome biology · 2012 · 2.4K citations · Full text

, , +17

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

Junjie U. Guo, Yijing Su, Chun Zhong et al. · Cell · 2011 · 1.4K citations · Full text

, , +14

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

Gabriella Ficz, Miguel R. Branco, Stefanie Seisenberger et al. · Nature · 2011 · 1.1K citations

, , +14

1–5 of 593

Authors

3.6K

  1. CH
    Chuan He

    University of Chicago, United States

    21 publications · 6.8K citations

    21

    h-index

  2. CS
    Chun‐Xiao Song

    University of Chicago, United States

    13 publications · 6K citations

    13

    h-index

  3. PJ
    Peng Jin

    Emory University, United States

    12 publications · 3.1K citations

    12

    h-index

  4. QD
    Qing Dai

    University of Chicago, United States

    12 publications · 5.7K citations

    12

    h-index

  5. BY
    Bi‐Feng Yuan

    Wuhan University, China

    12 publications · 724 citations

    12

    h-index

1–5 of 3.6K

Institutions

1K

  1. University of Chicago

    Chicago, United States

    26 h-index

    118 publications

    37.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    17 h-index

    42 publications

    18.8K citations

  3. Emory University

    Atlanta, United States

    17 h-index

    88 publications

    16.9K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    16 h-index

    70 publications

    16K citations

  5. Chinese Academy of Sciences

    Beijing, China

    16 h-index

    76 publications

    26K citations

  6. Wuhan University

    Wuhan, China

    16 h-index

    112 publications

    5.1K citations

  7. Ludwig-Maximilians-Universität München

    Munich, Germany

    15 h-index

    80 publications

    22.2K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    83 publications

    5.6K citations

1–8 of 1K

Venues

  1. Nucleic Acids Research

    28 publications · 2.9K citations

    25

    h-index

  2. Nature Communications

    18 publications · 1.7K citations

    18

    h-index

  3. Scientific Reports

    18 publications · 611 citations

    17

    h-index

  4. Epigenetics

    19 publications · 733 citations

    15

    h-index

  5. PLoS ONE

    14 publications · 1K citations

    13

    h-index

1–5