Disease Progression Modeling

Disease Progression Modeling is a computational and mathematical framework within systems medicine that characterizes the temporal evolution of pathological and clinical manifestations of a disease, distinguishing itself from related modeling approaches by explicitly representing the underlying biological mechanisms and clinical outcomes over time.

1.7K

Publications

95.1K

Citations

8.5K

Authors

2.7K

Institutions

Publications per year

2017–2026

825

Parents

Pharmacoeconomic ModelingPharmacokinetic-pharmacodynamic ModelingSystems Medicine

Children

Biomarker-based Progression ModelingCompartmental Disease ModelsDisease Natural History ModelingDynamic Disease ModelingForecasting Disease TrajectoriesHierarchical Disease ModelsIndividual Patient SimulationLongitudinal Disease ModelingMarkov Disease ModelsPatient State Trajectory Modeling

Publications

1.7K

Mathematical Analysis of HIV-1 Dynamics in Vivo

Alan S. Perelson, Patrick W. Nelson · SIAM Review · 1999 · 1.6K citations

Life Sciences, Immunology, Infectious Diseases +17

Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence

James P. Boyle, Theodore J. Thompson, Edward W. Gregg et al. · Population Health Metrics · 2010 · 1.3K citations · Full text

Public Health, Chronic Disease Prevention, Preventive Medicine +17

Multi-State Models for Panel Data: The<b>msm</b>Package for<i>R</i>

Christopher Jackson · Journal of Statistical Software · 2011 · 1.2K citations · Full text

Public Health, Biostatistics, Disease Surveillance +14

An Introduction to Recursive Partitioning Using the RPART Routines

Terry M. Therneau, Elizabeth J. Atkinson · 2015 · 1K citations

Computing, Biostatistics, Computational Biology +10

Integrative molecular concept modeling of prostate cancer progression

Scott A. Tomlins, Rohit Mehra, Daniel R. Rhodes et al. · Nature Genetics · 2006 · 937 citations

Medicine, Molecular Biology, Oncology +14

1–5 of 1.7K

Authors

8.5K

DC
Daniel C. Alexander
University College London, United Kingdom
15 publications · 1.2K citations
15
h-index
LC
Luonan Chen
Chinese Academy of Sciences, China
14 publications · 1.8K citations
14
h-index
KA
Kazuyuki Aihara
The University of Tokyo, Japan
14 publications · 1.6K citations
13
h-index
RL
Rui Liu
South China University of Technology, China
12 publications · 2K citations
12
h-index
AF
Avner Friedman
The Ohio State University, United States
11 publications · 605 citations
11
h-index

1–5 of 8.5K

Institutions

2.7K

1–8 of 2.7K

Venues

PLoS ONE
58 publications · 2.3K citations
28
h-index
Statistics in Medicine
58 publications · 2.3K citations
27
h-index
Scientific Reports
35 publications · 2.2K citations
23
h-index
PubMed
Repository · 28 publications · 1.5K citations
21
h-index
Biometrics
28 publications · 2K citations
20
h-index

1–5