Concepedia

Differential Pathway Activity Analysis

Differential Pathway Activity Analysis is a computational method in systems biology that identifies statistically significant changes in the activity levels of biological pathways between distinct experimental conditions or phenotypic states.

21

Publications

17.7K

Citations

138

Authors

56

Institutions

Publications per year

2017–2026

7

Parents

Publications

21

GSVA: gene set variation analysis for microarray and RNA-Seq data

Sonja Hänzelmann, Robert Castelo, Justin Guinney · BMC Bioinformatics · 2013 · 16.5K citations · Full text

, , +17

Pathway level analysis of gene expression using singular value decomposition

John K. Tomfohr, Jun Lü, Thomas B. Kepler · BMC Bioinformatics · 2005 · 450 citations · Full text

, , +10

A High Notch Pathway Activation Predicts Response to γ Secretase Inhibitors in Proneural Subtype of Glioma Tumor-Initiating Cells

Norihiko Saito, Jun Fu, Siyuan Zheng et al. · Stem Cells · 2013 · 128 citations · Full text

, , +17

Analysis of sample set enrichment scores: assaying the enrichment of sets of genes for individual samples in genome-wide expression profiles

Elena J. Edelman, Alessandro Porrello, Justin Guinney et al. · Bioinformatics · 2006 · 77 citations · Full text

, , +17

Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types

Anja van de Stolpe, Laurent Holtzer, Henk van Ooijen et al. · Scientific Reports · 2019 · 67 citations · Full text

, , +15

1–5 of 21

Authors

138

  1. SM
    Sayan Mukherjee

    Duke University, United States

    2 publications · 136 citations

    2

    h-index

  2. JG
    Justin Guinney

    Sage Bionetworks, United States

    2 publications · 16.6K citations

    2

    h-index

  3. JZ
    Jun Zhou

    Cornell University, United States

    1 publications · 49 citations

    1

    h-index

  4. MO
    Meric Ovacik

    Rutgers, The State University of New Jersey, United States

    1 publications · 19 citations

    1

    h-index

  5. WV
    Wim Verhaegh

    Philips (Netherlands), Netherlands

    1 publications · 67 citations

    1

    h-index

1–5 of 138

Institutions

56

  1. Duke University

    Durham, United States

    3 h-index

    11 publications

    1.9K citations

  2. Environmental Protection Agency

    Washington, United States

    2 h-index

    4 publications

    106 citations

  3. Georgia Institute of Technology

    Atlanta, United States

    1 h-index

    1 publications

    13 citations

  4. University of Miami

    Coral Gables, United States

    1 h-index

    1 publications

    13 citations

  5. Heilongjiang Institute of Technology

    Harbin, China

    1 h-index

    3 publications

    45 citations

  6. Lomonosov Moscow State University

    Moscow, Russia

    1 h-index

    2 publications

    34 citations

  7. Philips (Netherlands)

    Amsterdam, The Netherlands

    1 h-index

    5 publications

    335 citations

  8. Lund University

    Lund, Sweden

    1 h-index

    4 publications

    176 citations

1–8 of 56

Venues

  1. BMC Bioinformatics

    3 publications · 17K citations

    3

    h-index

  2. Bioinformatics

    2 publications · 136 citations

    2

    h-index

  3. Scientific Reports

    2 publications · 126 citations

    2

    h-index

  4. npj Biofilms and Microbiomes

    1 publications · 20 citations

    1

    h-index

  5. PROTEOMICS

    1 publications · 17 citations

    1

    h-index

1–5