Concepedia

Determinants Of Substrate Selectivity

Determinants of Substrate Selectivity is a biochemical concept that refers to the specific molecular features and structural properties of an enzyme or catalyst that govern its preferential recognition and binding of particular substrates over others within a complex mixture.

437

Publications

21K

Citations

2K

Authors

603

Institutions

Publications per year

2017–2026

121

Parents

Publications

437

Identification and Functional Characterization of a Na+-independent Neutral Amino Acid Transporter with Broad Substrate Selectivity

Hiroko Segawa, Yoshiki Fukasawa, Ken‐ichi Miyamoto et al. · Journal of Biological Chemistry · 1999 · 500 citations · Full text

, , +13

Multiubiquitin Chain Receptors Define a Layer of Substrate Selectivity in the Ubiquitin-Proteasome System

Rati Verma, Robert Oania, Johannes Graumann et al. · Cell · 2004 · 453 citations · Full text

, , +16

Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases.

Fernando A. González, David Raden, Roger J. Davis · Journal of Biological Chemistry · 1991 · 450 citations · Full text

, , +16

Phylogenetic and functional analysis of the Cation Diffusion Facilitator (CDF) family: improved signature and prediction of substrate specificity

Barbara Montanini, Damien Blaudez, Sylvain Jeandroz et al. · BMC Genomics · 2007 · 424 citations · Full text

, , +13

NBR1 acts as an autophagy receptor for peroxisomes

Elizabeth Deosaran, Kenneth Bowitz Larsen, Rong Hua et al. · Journal of Cell Science · 2012 · 354 citations

, , +15

1–5 of 437

Authors

2K

  1. CJ
    Christopher J. Schofield

    University of Oxford, United Kingdom

    11 publications · 543 citations

    11

    h-index

  2. MM
    M.A. McDonough

    University of Oxford, United Kingdom

    5 publications · 180 citations

    5

    h-index

  3. CA
    Carol A. Fierke

    University of Michigan, United States

    4 publications · 119 citations

    4

    h-index

  4. RJ
    Robert J. Vandenberg

    The University of Sydney, Australia

    4 publications · 159 citations

    4

    h-index

  5. TD
    Timothy D. W. Claridge

    University of Oxford, United Kingdom

    4 publications · 117 citations

    4

    h-index

1–5 of 2K

Institutions

603

  1. University of Michigan

    Ann Arbor, United States

    13 h-index

    43 publications

    1.7K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    34 publications

    4.4K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    46 publications

    2.2K citations

  4. Chinese Academy of Sciences

    Beijing, China

    11 h-index

    51 publications

    2.6K citations

  5. University of Oxford

    Oxford, United Kingdom

    10 h-index

    77 publications

    3.9K citations

  6. University of California San Diego

    San Diego, United States

    9 h-index

    19 publications

    1.2K citations

  7. Cornell University

    Ithaca, United States

    7 h-index

    22 publications

    970 citations

  8. Harvard University

    Cambridge, United States

    7 h-index

    29 publications

    1.4K citations

1–8 of 603

Venues

  1. Journal of Biological Chemistry

    JBC · 42 publications · 3.7K citations

    29

    h-index

  2. Biochemistry

    41 publications · 1.5K citations

    24

    h-index

  3. Journal of the American Chemical Society

    JACS · 18 publications · 870 citations

    16

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 19 publications · 1.1K citations

    16

    h-index

  5. Nature Communications

    12 publications · 637 citations

    13

    h-index

1–5