Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines

Osamu Yanagida, Yoshikatsu Kanai, Arthit Chairoungdua, +17

Biochimica et Biophysica Acta (BBA) - Biomembranes

Signal TransductionBiochemistryOncogenic AgentMedicineMembrane Transport +9

Identification and Functional Characterization of a Na+-independent Neutral Amino Acid Transporter with Broad Substrate Selectivity

Hiroko Segawa, Yoshiki Fukasawa, Ken‐ichi Miyamoto, +3

Journal of Biological Chemistry

Substrate SelectivityProtein ChemistryMolecular PhysiologyBiochemistryMedicine +10

Identification and Characterization of a Na+-independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral d- and l-Amino Acids

Yoshiki Fukasawa, Hiroko Segawa, Ju Young Kim, +6

Journal of Biological Chemistry

(1<i>S</i>)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-<scp>d</scp>-glucitol (TS-071) is a Potent, Selective Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for Type 2 Diabetes Treatment

Hiroyuki Kakinuma, Takahiro Oi, Yuko Hashimoto-Tsuchiya, +15

Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryDiabetes ManagementBiochemistryCompound 3P +11

Transport Properties of a System y+L Neutral and Basic Amino Acid Transporter

Yoshikatsu Kanai, Yoshiki Fukasawa, Seok Ho, +8

Journal of Biological Chemistry

mRNA Expression and Amino Acid Transport Characteristics of Cultured Human Brain Microvascular Endothelial Cells (hBME)

Nobuo Umeki, Yoshiki Fukasawa, Sumio Ohtsuki, +4

Drug Metabolism and Pharmacokinetics

Preclinical metabolism and disposition of luseogliflozin, a novel antihyperglycemic agent

Masatoshi Hasegawa, Yukihiro Chino, Nobuko Horiuchi, +5

Xenobiotica

Gastrointestinal PharmacologyRenal RadioactivityExperimental PharmacologyOxidative StressDrug-derived Radioactivity +17

IN VITRO AND IN VIVO EVALUATION OF THE METABOLISM AND BIOAVAILABILITY OF ESTER PRODRUGS OF MGS0039 (3-(3,4-DICHLOROBENZYLOXY)-2-AMINO-6-FLUOROBICYCLO[3.1.0]HEXANE-2,6-DICARBOXYLIC ACID), A POTENT METABOTROPIC GLUTAMATE RECEPTOR ANTAGONIST

Masato Nakamura, Yasunori Kawakita, Akito Yasuhara, +4

Drug Metabolism and Disposition

Lymphopenia induced by a novel selective S1P1 antagonist structurally unrelated to S1P

Yasuyuki Fujii, Hidenori Ohtake, Naoya Ono, +10

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Autoimmune DiseaseMedicineImmunologyLymphatic SystemLymphatic Disease +3

Pharmacokinetic and Pharmacodynamic Studies of Centrally Acting Drugs in Rat: Effect of Pentobarbital and Chlorpromazine on Electroencephalogram in Rat.

Shinji Sato, Akira Koshiro, Masawo Kakemi, +3

Biological and Pharmaceutical Bulletin

NeuropsychologyNeurophysiological BiomarkersPharmacotherapyExperimental PharmacologyPharmacodynamic Studies +22