Concepedia

Damp-driven Inflammation

Damp-Driven Inflammation is a pathophysiological mechanism within the context of inflammatory tissue injury characterized by the accumulation of metabolic byproducts and fluidic imbalances that promote chronic inflammatory responses through dysregulated immune activation and impaired tissue clearance.

88

Publications

9.7K

Citations

677

Authors

261

Institutions

Publications per year

2017–2026

47

Parents

Publications

88

Circulating mitochondrial DAMPs cause inflammatory responses to injury

Qin Zhang, Mustafa Raoof, Yu Chen et al. · Nature · 2010 · 3.7K citations · Full text

, , +12

MD-2 is required for disulfide HMGB1–dependent TLR4 signaling

Huan Yang, Haichao Wang, Zhongliang Ju et al. · The Journal of Experimental Medicine · 2015 · 368 citations · Full text

, , +17

DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury

Arthur Liesz, Alexander H. Dalpke, Éva Mracskó et al. · Journal of Neuroscience · 2015 · 332 citations · Full text

, , +17

Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation

Thomas Vogl, Athanasios Stratis, Viktor Wixler et al. · Journal of Clinical Investigation · 2018 · 230 citations · Full text

, , +17

DAMP Molecule S100A9 Acts as a Molecular Pattern to Enhance Inflammation during Influenza A Virus Infection: Role of DDX21-TRIF-TLR4-MyD88 Pathway

Su-Yu Tsai, Jesus A. Segovia, Te-Hung Chang et al. · PLoS Pathogens · 2014 · 199 citations · Full text

, , +17

1–5 of 88

Authors

677

  1. TR
    Timothy R. Billiar

    University of Pittsburgh, United States

    3 publications · 542 citations

    3

    h-index

  2. YV
    Yoram Vodovotz

    University of Pittsburgh, United States

    3 publications · 204 citations

    3

    h-index

  3. RZ
    Rubén Zamora

    University of Pittsburgh, United States

    3 publications · 204 citations

    3

    h-index

  4. YA
    Yousef Al‐Abed

    Feinstein Institute for Medical Research, United States

    2 publications · 389 citations

    2

    h-index

  5. DO
    DO Okonkwo

    University of Pittsburgh, United States

    2 publications · 148 citations

    2

    h-index

1–5 of 677

Institutions

261

  1. Inserm

    Paris, France

    6 h-index

    17 publications

    576 citations

  2. University of Pittsburgh

    Pittsburgh, United States

    6 h-index

    25 publications

    2.6K citations

  3. Feinstein Institute for Medical Research

    Manhasset, United States

    4 h-index

    19 publications

    4.9K citations

  4. University Medical Center Groningen

    Groningen, The Netherlands

    3 h-index

    25 publications

    2.9K citations

  5. Harvard University

    Cambridge, United States

    3 h-index

    22 publications

    28.2K citations

  6. The University of Tokyo

    Tokyo, Japan

    3 h-index

    30 publications

    4.2K citations

  7. Columbia University

    New York, United States

    3 h-index

    11 publications

    408 citations

  8. University of Groningen

    Groningen, The Netherlands

    3 h-index

    25 publications

    2.9K citations

1–8 of 261

Venues

  1. PLoS ONE

    6 publications · 331 citations

    6

    h-index

  2. Frontiers in Immunology

    5 publications · 166 citations

    5

    h-index

  3. PubMed

    Repository · 3 publications · 112 citations

    3

    h-index

  4. Nature

    2 publications · 3.9K citations

    2

    h-index

  5. Journal of Neuroinflammation

    JNI · 2 publications · 95 citations

    2

    h-index

1–5