Concepedia

Crystallin Disorders

Crystallin Disorders is a pathological condition characterized by structural and functional abnormalities in crystallin proteins within the ocular lens, leading to impaired transparency and contributing to the development of cataracts.

129

Publications

7.7K

Citations

551

Authors

185

Institutions

Publications per year

2017–2026

25

Parents

Publications

129

αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

Toru Iwaki, A. Kume-Iwaki, Ronald K.H. Liem et al. · Cell · 1989 · 553 citations

, , +8

Human αB-Crystallin Mutation Causes Oxido-Reductive Stress and Protein Aggregation Cardiomyopathy in Mice

Namakkal S. Rajasekaran, Patrice M. Connell, Elisabeth Christians et al. · Cell · 2007 · 433 citations · Full text

, , +7

Mutation R120G in αB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

Michael P. Bova, Orna Yaron, Qingling Huang et al. · Proceedings of the National Academy of Sciences · 1999 · 371 citations · Full text

, , +17

Expression of R120G–αB-Crystallin Causes Aberrant Desmin and αB-Crystallin Aggregation and Cardiomyopathy in Mice

Xuejun Wang, Hanna Osińska, Raisa Klevitsky et al. · Circulation Research · 2001 · 320 citations · Full text

, , +14

The γ-Crystallins and Human Cataracts: A Puzzle Made Clearer

Élise Héon, Megan Priston, Daniel F. Schorderet et al. · The American Journal of Human Genetics · 1999 · 251 citations · Full text

, , +10

1–5 of 129

Authors

551

  1. YY
    Yong‐Bin Yan

    Tsinghua University, China

    10 publications · 244 citations

    10

    h-index

  2. KY
    Ke Yao

    Second Affiliated Hospital of Zhejiang University, China

    10 publications · 218 citations

    10

    h-index

  3. UP
    Usha P. Andley

    Washington University in St. Louis, United States

    7 publications · 379 citations

    7

    h-index

  4. JG
    Jochen Graw

    Helmholtz Zentrum München, Germany

    7 publications · 590 citations

    7

    h-index

  5. RY
    Reza Yousefi

    Shiraz University, Iran

    7 publications · 172 citations

    7

    h-index

1–5 of 551

Institutions

185

  1. Tsinghua University

    Beijing, China

    10 h-index

    42 publications

    1K citations

  2. Zhejiang University

    Hangzhou, China

    8 h-index

    16 publications

    349 citations

  3. Shiraz University

    Shiraz, Iran

    7 h-index

    20 publications

    438 citations

  4. Washington University in St. Louis

    St Louis, United States

    6 h-index

    11 publications

    817 citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    5 h-index

    18 publications

    1.9K citations

  6. Institute of Groundwater Ecology

    Landau, Germany

    5 h-index

    25 publications

    1.5K citations

  7. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    5 h-index

    14 publications

    385 citations

  8. Second Affiliated Hospital of Zhejiang University

    Hangzhou, China

    5 h-index

    23 publications

    418 citations

1–8 of 185

Venues

  1. PubMed

    Repository · 13 publications · 633 citations

    11

    h-index

  2. PLoS ONE

    10 publications · 344 citations

    10

    h-index

  3. Biochemical and Biophysical Research Communications

    BBRC · 8 publications · 328 citations

    8

    h-index

  4. Journal of Biological Chemistry

    JBC · 8 publications · 539 citations

    7

    h-index

  5. Experimental Eye Research

    6 publications · 277 citations

    6

    h-index

1–5