Concepedia

Copy Number Amplification

Copy Number Amplification is a type of copy number alteration characterized by an increase in the number of copies of a specific genomic region beyond the normal diploid state, typically resulting in gene overexpression and associated with oncogenic activation in cancer genomes.

459

Publications

34.6K

Citations

3.9K

Authors

1K

Institutions

Publications per year

2017–2026

159

Parents

Publications

459

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

Daniel C. Koboldt, Qunyuan Zhang, David E. Larson et al. · Genome Research · 2012 · 5.3K citations · Full text

, , +17

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

Jonathan R. Pollack, Thérese Sørlie, Charles M. Perou et al. · Proceedings of the National Academy of Sciences · 2002 · 1.1K citations

, , +17

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization.

Anne Kallioniemi, Olli Kallioniemi, Jim Piper et al. · Proceedings of the National Academy of Sciences · 1994 · 748 citations

, , +17

DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies.

Sakari Knuutila, A-M Björkqvist, K. Autio et al. · PubMed · 1998 · 574 citations

, , +16

Impact of DNA amplification on gene expression patterns in breast cancer.

Elizabeth Hyman, Päivikki Kauraniemi, Sampsa Hautaniemi et al. · PubMed · 2002 · 493 citations

, , +17

1–5 of 459

Authors

3.9K

  1. OM
    Outi Monni

    University of Helsinki, Finland

    9 publications · 2.1K citations

    9

    h-index

  2. SK
    Sakari Knuutila

    University of Helsinki, Finland

    8 publications · 1.1K citations

    8

    h-index

  3. AK
    Anne Kallioniemi

    7 publications · 2.1K citations

    7

    h-index

  4. MW
    Maija Wolf

    University of Helsinki, Finland

    6 publications · 1.8K citations

    6

    h-index

  5. RB
    Rameen Beroukhim

    Dana-Farber Cancer Institute, United States

    5 publications · 872 citations

    5

    h-index

1–5 of 3.9K

Institutions

1K

  1. Harvard University

    Cambridge, United States

    13 h-index

    93 publications

    13.5K citations

  2. University of Helsinki

    Helsinki, Finland

    13 h-index

    43 publications

    4.7K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    12 h-index

    67 publications

    11.3K citations

  4. University of California, San Francisco

    San Francisco, United States

    11 h-index

    53 publications

    8.2K citations

  5. Johns Hopkins University

    Baltimore, United States

    11 h-index

    56 publications

    3.5K citations

  6. Helsinki University Hospital

    Helsinki, Finland

    11 h-index

    31 publications

    3K citations

  7. Brigham and Women's Hospital

    Boston, United States

    10 h-index

    65 publications

    10.8K citations

  8. The University of Texas MD Anderson Cancer Center

    Houston, United States

    9 h-index

    51 publications

    1.3K citations

1–8 of 1K

Venues

  1. PubMed

    Repository · 29 publications · 3.8K citations

    24

    h-index

  2. Genes Chromosomes and Cancer

    27 publications · 1.6K citations

    20

    h-index

  3. PLoS ONE

    22 publications · 1.3K citations

    18

    h-index

  4. BMC Cancer

    10 publications · 585 citations

    10

    h-index

  5. Cancer Research

    10 publications · 1.2K citations

    10

    h-index

1–5