Concepedia

Contact System Coagulation

Contact System Coagulation is a physiological activation pathway within the intrinsic coagulation cascade that initiates blood clotting through the surface-dependent autoactivation of factor XII, prekallikrein, and high-molecular-weight kininogen in response to negatively charged surfaces.

212

Publications

11.6K

Citations

984

Authors

322

Institutions

Publications per year

2017–2026

34

Parents

Publications

212

Contaminated Heparin Associated with Adverse Clinical Events and Activation of the Contact System

Takashi Kishimoto, Karthik Viswanathan, Tanmoy Ganguly et al. · New England Journal of Medicine · 2008 · 616 citations · Full text

, , +12

Contact System: A Vascular Biology Modulator With Anticoagulant, Profibrinolytic, Antiadhesive, and Proinflammatory Attributes

Robert W. Colman, Alvin H. Schmaier · Blood · 1997 · 589 citations · Full text

, , +15

The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons.

Robin A. Pixley, RA De La Cadena, Jimmy D. Page et al. · Journal of Clinical Investigation · 1993 · 278 citations · Full text

, , +16

Misfolded proteins activate Factor XII in humans, leading to kallikrein formation without initiating coagulation

Coen Maas, José W.P. Govers‐Riemslag, Barend Bouma et al. · Journal of Clinical Investigation · 2008 · 242 citations

, , +17

Contact pathway of coagulation and inflammation

Yi Wu · Thrombosis Journal · 2015 · 199 citations · Full text

, , +15

1–5 of 212

Authors

984

  1. RW
    Robert W. Colman

    Temple University, United States

    12 publications · 1.7K citations

    12

    h-index

  2. HT
    Hugo Ten Cate

    Maastricht University, Netherlands

    9 publications · 632 citations

    10

    h-index

  3. JC
    Joost C.M. Meijers

    Amsterdam UMC Location University of Amsterdam, Netherlands

    10 publications · 401 citations

    10

    h-index

  4. BN
    Bonno N. Bouma

    Utrecht University, Netherlands

    9 publications · 722 citations

    9

    h-index

  5. HH
    Heiko Herwald

    Lund University, Sweden

    8 publications · 430 citations

    8

    h-index

1–5 of 984

Institutions

322

  1. Temple University

    Philadelphia, United States

    14 h-index

    57 publications

    5.8K citations

  2. University of Amsterdam

    Amsterdam, The Netherlands

    14 h-index

    63 publications

    3.9K citations

  3. Dutch Blood Transfusion Society

    Amsterdam, Netherlands

    14 h-index

    46 publications

    3.2K citations

  4. Lund University

    Lund, Sweden

    13 h-index

    42 publications

    1.9K citations

  5. Amsterdam UMC Location University of Amsterdam

    Amsterdam, The Netherlands

    10 h-index

    36 publications

    2K citations

  6. Utrecht University

    Utrecht, The Netherlands

    8 h-index

    28 publications

    2.3K citations

  7. University of Milan

    Milan, Italy

    7 h-index

    15 publications

    760 citations

  8. University of Michigan

    Ann Arbor, United States

    7 h-index

    22 publications

    2.6K citations

1–8 of 322

Venues

  1. Thrombosis and Haemostasis

    27 publications · 1.1K citations

    20

    h-index

  2. PubMed

    Repository · 14 publications · 675 citations

    13

    h-index

  3. Journal of Clinical Investigation

    JCI · 11 publications · 1.3K citations

    11

    h-index

  4. Blood

    10 publications · 1.1K citations

    10

    h-index

  5. Blood Coagulation & Fibrinolysis

    8 publications · 231 citations

    8

    h-index

1–5