Blood · 1997 · 589 citations · 275 references
MedicinePhysiologyCell AdhesionHemostasisInflammationEndothelial ActivationEndothelial Regulation Of HemostasisFibrin FormationPlatelet AdhesionPlatelet AggregationThrombosis PreventionAnticoagulant MechanismsContact System CoagulationEndothelial Contribution To ThrombosisEndothelial Procoagulant ActivityEndothelial Regulation Of CoagulationEndothelium-dependent Coagulation RegulationProinflammatory Mediators
physiologic reactions of vascular biology. Last, this presentation will point to possible new therapeutic strategies to treat HE KALLIKREIN-KININ system was first recognized as a plasma and tissue proteolytic system responsible for the liberation of the vasoactive, proinflammatory media-various diseases arising out of the knowledge of this system in physiologic and pathophysiologic states. tor, bradykinin (BK). 1 BK, a nonapeptide released from kininogens by kallikreins, could reproduce many of the charac-
275