Concepedia

Contact Pathway

Contact Pathway is a coagulation cascade mechanism that initiates thrombin generation through the activation of factor XII upon exposure to negatively charged surfaces, distinguishing it from tissue factor-dependent pathways.

161

Publications

9.2K

Citations

797

Authors

261

Institutions

Publications per year

2017–2026

34

Variants

Intrinsic Coagulation Pathway

Parents

Publications

161

Polyphosphate modulates blood coagulation and fibrinolysis

Stephanie A. Smith, Nicola J. Mutch, Deepak Baskar et al. · Proceedings of the National Academy of Sciences · 2006 · 548 citations · Full text

, , +17

Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation

Christian Kannemeier, Aya Shibamiya, Fumie Nakazawa et al. · Proceedings of the National Academy of Sciences · 2007 · 532 citations · Full text

, , +15

beta 2-Glycoprotein I: a plasma inhibitor of the contact activation of the intrinsic blood coagulation pathway

Inger Schousboe · Blood · 1985 · 363 citations · Full text

, , +15

The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons.

Robin A. Pixley, RA De La Cadena, Jimmy D. Page et al. · Journal of Clinical Investigation · 1993 · 278 citations · Full text

, , +16

Misfolded proteins activate Factor XII in humans, leading to kallikrein formation without initiating coagulation

Coen Maas, José W.P. Govers‐Riemslag, Barend Bouma et al. · Journal of Clinical Investigation · 2008 · 242 citations

, , +17

1–5 of 161

Authors

797

  1. JH
    James H. Morrissey

    University of Illinois Urbana-Champaign, United States

    9 publications · 860 citations

    9

    h-index

  2. SA
    Stephanie A. Smith

    University of Illinois Urbana-Champaign, United States

    9 publications · 860 citations

    9

    h-index

  3. DG
    David Gailani

    Vanderbilt University, United States

    6 publications · 382 citations

    6

    h-index

  4. HT
    Hugo Ten Cate

    Maastricht University, Netherlands

    6 publications · 367 citations

    6

    h-index

  5. SL
    Scott L. Diamond

    University of Pennsylvania, United States

    5 publications · 185 citations

    5

    h-index

1–5 of 797

Institutions

261

  1. Temple University

    Philadelphia, United States

    8 h-index

    31 publications

    2.8K citations

  2. University of Amsterdam

    Amsterdam, The Netherlands

    7 h-index

    27 publications

    1.4K citations

  3. University of Pennsylvania

    Philadelphia, United States

    7 h-index

    26 publications

    976 citations

  4. McMaster University

    Hamilton, Canada

    7 h-index

    25 publications

    1.9K citations

  5. University of Illinois Urbana-Champaign

    Urbana, United States

    7 h-index

    29 publications

    4.2K citations

  6. Dutch Blood Transfusion Society

    Amsterdam, Netherlands

    6 h-index

    18 publications

    1.1K citations

  7. Ludwig-Maximilians-Universität München

    Munich, Germany

    5 h-index

    7 publications

    723 citations

  8. University of Michigan

    Ann Arbor, United States

    4 h-index

    18 publications

    1.3K citations

1–8 of 261

Venues

  1. Thrombosis and Haemostasis

    20 publications · 1K citations

    17

    h-index

  2. Blood

    12 publications · 1K citations

    12

    h-index

  3. Thrombosis Research

    10 publications · 236 citations

    10

    h-index

  4. Blood Advances

    6 publications · 235 citations

    6

    h-index

  5. 5

    h-index

1–5