Concepedia

Conditional Allele Engineering

Conditional Allele Engineering is a genetic engineering methodology that enables the precise spatial and temporal control of gene modification through the incorporation of recombinase recognition sites flanking critical gene segments, thereby allowing targeted allele alteration in specific cell types or developmental stages.

125

Publications

8.6K

Citations

796

Authors

251

Institutions

Publications per year

2017–2026

20

Parents

Publications

125

Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in <i>Drosophila</i>

Scott J. Gratz, Fiona P. Ukken, C. Dustin Rubinstein et al. · Genetics · 2014 · 1.1K citations · Full text

, , +17

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

Iris T. Chan, Jeffery L. Kutok, Ifor R. Williams et al. · Journal of Clinical Investigation · 2004 · 261 citations · Full text

, , +17

Epidermal Cell Fate Determination in <i>Arabidopsis</i> : Patterns Defined by a Steroid-Inducible Regulator

Alan Lloyd, Mark Schena, Virginia Walbot et al. · Science · 1994 · 249 citations

, , +17

Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types

Jacqueline A. Walisser, Edward Glover, Kalyan Pande et al. · Proceedings of the National Academy of Sciences · 2005 · 234 citations · Full text

, , +17

Dicer1 Is Required for Differentiation of the Mouse Male Germline1

Danielle M. Maatouk, Kate L. Loveland, Michael T. McManus et al. · Biology of Reproduction · 2008 · 219 citations · Full text

, , +17

1–5 of 125

Authors

796

  1. TJ
    Tyler Jacks

    Massachusetts Institute of Technology, United States

    4 publications · 367 citations

    4

    h-index

  2. DA
    David A. Tuveson

    Cold Spring Harbor Laboratory, United States

    3 publications · 335 citations

    3

    h-index

  3. MD
    Matthew D. Breyer

    Vanderbilt University, United States

    3 publications · 129 citations

    3

    h-index

  4. VK
    Vladimír Kořínek

    Czech Academy of Sciences, Institute of Molecular Genetics, Czechia

    2 publications · 75 citations

    2

    h-index

  5. KS
    Kenji Sakimura

    Niigata University, Japan

    2 publications · 84 citations

    2

    h-index

1–5 of 796

Institutions

251

  1. Massachusetts Institute of Technology

    Cambridge, United States

    7 h-index

    23 publications

    1.2K citations

  2. Harvard University

    Cambridge, United States

    7 h-index

    18 publications

    1.5K citations

  3. University of California San Diego

    San Diego, United States

    6 h-index

    18 publications

    1.3K citations

  4. National Institutes of Health

    Bethesda, United States

    5 h-index

    26 publications

    1.3K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    15 publications

    491 citations

  6. University of Pennsylvania

    Philadelphia, United States

    5 h-index

    11 publications

    639 citations

  7. The University of Texas MD Anderson Cancer Center

    Houston, United States

    5 h-index

    23 publications

    1.7K citations

  8. University of California, San Francisco

    San Francisco, United States

    5 h-index

    22 publications

    2.1K citations

1–8 of 251

Venues

  1. genesis

    28 publications · 1.1K citations

    22

    h-index

  2. PLoS ONE

    12 publications · 323 citations

    11

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 1K citations

    9

    h-index

  4. Molecular and Cellular Biology

    MCB · 6 publications · 569 citations

    6

    h-index

  5. Genetics

    4 publications · 1.3K citations

    4

    h-index

1–5