Concepedia

Compound Series Analysis

Compound Series Analysis is a systematic methodological framework within medicinal chemistry that identifies and evaluates localized structure-activity relationships by analyzing abrupt changes in biological potency among structurally similar compounds, particularly focusing on activity cliffs within congeneric series.

122

Publications

4.3K

Citations

514

Authors

162

Institutions

Publications per year

2017–2026

26

Parents

Publications

122

Large-scale comparison of machine learning methods for drug target prediction on ChEMBL

Andreas Mayr, Günter Klambauer, Thomas Unterthiner et al. · Chemical Science · 2018 · 600 citations · Full text

, , +15

6-Phenyl-4,5-dihydro-3(2H)-pyridazinones. Series of hypotensive agents

William V. Curran, Adma Ross · Journal of Medicinal Chemistry · 1974 · 109 citations

, , +8

An updated review on diverse range of biological activities of 1,2,4-triazole derivatives: Insight into structure activity relationship

Ojasvi Gupta, Tathagata Pradhan, Gita Chawla · Journal of Molecular Structure · 2022 · 100 citations

, , +17

Alanine series of ovine corticotropin releasing factor (oCRF): a structure-activity relationship study

Wayne D. Kornreich, Robert Galyean, A. Grey Craig et al. · Journal of Medicinal Chemistry · 1992 · 91 citations

, , +8

QSARs for organotin compounds on Daphnia magna

Marco Vighi, D. Calamari · Chemosphere · 1985 · 88 citations

, , +10

1–5 of 122

Authors

514

  1. JB
    Jürgen Bajorath

    University of Bonn, Germany

    11 publications · 316 citations

    10

    h-index

  2. DS
    Dagmar Stumpfe

    University of Bonn, Germany

    3 publications · 125 citations

    3

    h-index

  3. DG
    Disha Gupta‐Ostermann

    University of Bonn, Germany

    3 publications · 56 citations

    3

    h-index

  4. IH
    Ian H. Gilbert

    University of Dundee, United Kingdom

    3 publications · 89 citations

    3

    h-index

  5. SP
    Stuart P. McElroy

    University of Dundee, United Kingdom

    2 publications · 79 citations

    2

    h-index

1–5 of 514

Institutions

162

  1. University of Bonn

    Bonn, Germany

    9 h-index

    24 publications

    749 citations

  2. National Cancer Institute

    Bethesda, United States

    3 h-index

    18 publications

    971 citations

  3. University of Dundee

    Dundee, United Kingdom

    3 h-index

    27 publications

    857 citations

  4. Babeș-Bolyai University

    Cluj-Napoca, Romania

    2 h-index

    5 publications

    172 citations

  5. University of Copenhagen

    Copenhagen, Denmark

    2 h-index

    9 publications

    117 citations

  6. Bayer (Germany)

    Leverkusen, Germany

    2 h-index

    2 publications

    627 citations

  7. Maharshi Dayanand University

    Rohtak, India

    2 h-index

    2 publications

    94 citations

  8. University of Illinois Chicago

    Chicago, United States

    2 h-index

    2 publications

    141 citations

1–8 of 162

Venues

  1. Journal of Medicinal Chemistry

    18 publications · 714 citations

    15

    h-index

  2. Journal of Chemical Information and Modeling

    JCIM · 8 publications · 293 citations

    8

    h-index

  3. Journal of the American Chemical Society

    JACS · 8 publications · 208 citations

    8

    h-index

  4. F1000Research

    3 publications · 118 citations

    3

    h-index

  5. The Journal of Organic Chemistry

    JOC · 3 publications · 65 citations

    3

    h-index

1–5