Concepedia

Complement Protein Structure - Function Relationships

Complement Protein Structure - Function Relationships is a biochemical construct that delineates the mechanistic interdependence between the three-dimensional architectural features of complement proteins and their immunological activities within the innate immune cascade.

630

Publications

41.6K

Citations

1.7K

Authors

501

Institutions

Publications per year

2017–2026

29

Parents

Publications

630

The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor

Lawrence Shapiro, Philipp E. Scherer · Current Biology · 1998 · 656 citations · Full text

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Structures of complement component C3 provide insights into the function and evolution of immunity

B.J.C. Janssen, Eric G. Huizinga, H.C.A. Raaijmakers et al. · Nature · 2005 · 548 citations · Full text

, , +12

Molecular Basis of Complement Action

Ralph E. Thorson, Herbert J. Rapp, Tibor Borsos · Journal of Parasitology · 1971 · 520 citations · Full text

, , +12

The structural basis of the multiple forms of human complement component C4

Katharina Belt, Michael C. Carroll, Rodney R. Porter · Cell · 1984 · 421 citations

, , +8

Characterization of C-reactive protein and the complement subcomponent C1t as homologous proteins displaying cyclic pentameric symmetry (pentraxins).

Alexander P. Osmand, Bernard Friedenson, H Gewurz et al. · Proceedings of the National Academy of Sciences · 1977 · 375 citations · Full text

, , +11

1–5 of 630

Authors

1.7K

  1. JD
    John D. Lambris

    University of Pennsylvania, United States

    31 publications · 2.6K citations

    28

    h-index

  2. PN
    Paul N. Barlow

    University of Edinburgh, United Kingdom

    36 publications · 2.8K citations

    26

    h-index

  3. SJ
    Stephen J. Perkins

    University College London, United Kingdom

    30 publications · 1.4K citations

    23

    h-index

  4. DE
    David E. Isenman

    University of Toronto, Canada

    22 publications · 2K citations

    20

    h-index

  5. GJ
    Gérard J. Arlaud

    Institut de Biologie Structurale, France

    19 publications · 1.5K citations

    18

    h-index

1–5 of 1.7K

Institutions

501

  1. University of Oxford

    Oxford, United Kingdom

    34 h-index

    171 publications

    14.7K citations

  2. University of Pennsylvania

    Philadelphia, United States

    25 h-index

    96 publications

    8.2K citations

  3. University of Edinburgh

    Edinburgh, United Kingdom

    25 h-index

    139 publications

    10.3K citations

  4. Lund University

    Lund, Sweden

    23 h-index

    95 publications

    5.5K citations

  5. Washington University in St. Louis

    St Louis, United States

    22 h-index

    83 publications

    5.6K citations

  6. University of Toronto

    Toronto, Canada

    21 h-index

    75 publications

    5.6K citations

  7. University College London

    London, United Kingdom

    21 h-index

    85 publications

    4K citations

  8. University of South Carolina

    Columbia, United States

    18 h-index

    70 publications

    2.5K citations

1–8 of 501

Venues

  1. The Journal of Immunology

    JI · 100 publications · 7K citations

    52

    h-index

  2. Journal of Biological Chemistry

    JBC · 92 publications · 5.8K citations

    50

    h-index

  3. Biochemistry

    48 publications · 2.9K citations

    33

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 35 publications · 4.1K citations

    31

    h-index

  5. Journal of Molecular Biology

    JMB · 31 publications · 2K citations

    27

    h-index

1–5