Concepedia

Cohesion Fatigue

Cohesion fatigue is a mitotic chromosome behavior in which prolonged bipolar attachment of chromosomes to the spindle microtubules during metaphase leads to the gradual loss of sister chromatid cohesion prior to anaphase onset, resulting in premature chromatid separation.

11

Publications

661

Citations

72

Authors

42

Institutions

Publications per year

2017–2026

7

Parents

Publications

11

Cohesion Fatigue Induces Chromatid Separation in Cells Delayed at Metaphase

John R. Daum, Tamara Potapova, Sushama Sivakumar et al. · Current Biology · 2011 · 171 citations · Full text

, , +11

Non-random Mis-segregation of Human Chromosomes

Joseph T Worrall, Naoka Tamura, Alice Mazzagatti et al. · Cell Reports · 2018 · 130 citations · Full text

, , +17

The spindle and kinetochore–associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit

Sushama Sivakumar, John R. Daum, Aaron R. Tipton et al. · Molecular Biology of the Cell · 2014 · 74 citations · Full text

, , +17

Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function

Job de Lange, Atiq Faramarz, Anneke B. Oostra et al. · Nature Communications · 2015 · 56 citations · Full text

, , +17

Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection

V. Pragathi Masamsetti, Ronnie Ren Jie Low, Ka Sin Mak et al. · Nature Communications · 2019 · 56 citations · Full text

, , +17

1–5 of 11

Authors

72

  1. GJ
    Gary J. Gorbsky

    Oklahoma Medical Research Foundation, United States

    3 publications · 276 citations

    3

    h-index

  2. JR
    John R. Daum

    Oklahoma Medical Research Foundation, United States

    3 publications · 276 citations

    3

    h-index

  3. MA
    Martin A. Rooimans

    Amsterdam UMC Location Vrije Universiteit Amsterdam, Netherlands

    2 publications · 84 citations

    2

    h-index

  4. AB
    Anneke B. Oostra

    Amsterdam UMC Location Vrije Universiteit Amsterdam, Netherlands

    2 publications · 84 citations

    2

    h-index

  5. RM
    Rob M.F. Wolthuis

    The Netherlands Cancer Institute, Netherlands

    2 publications · 84 citations

    2

    h-index

1–5 of 72

Institutions

42

  1. Oklahoma Medical Research Foundation

    Oklahoma City, United States

    3 h-index

    12 publications

    1.2K citations

  2. University of Oklahoma Health Sciences Center

    Oklahoma City, United States

    3 h-index

    10 publications

    1.1K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    7 publications

    230 citations

  4. Medical University of Vienna

    Vienna, Austria

    1 h-index

    1 publications

    24 citations

  5. Max Perutz Labs

    Vienna, Austria

    1 h-index

    3 publications

    72 citations

  6. Université Fédérale de Toulouse Midi-Pyrénées

    Toulouse, France

    1 h-index

    1 publications

    56 citations

  7. CEA Paris-Saclay

    Gif-sur-Yvette, France

    1 h-index

    1 publications

    56 citations

  8. Paracelsus Medical University

    Salzburg, Austria

    1 h-index

    3 publications

    84 citations

1–8 of 42

Venues

  1. Nature Communications

    3 publications · 141 citations

    3

    h-index

  2. Molecular Biology of the Cell

    MBC · 2 publications · 105 citations

    2

    h-index

  3. Sapientia (Algarve University)

    Repository · 1 publications · 28 citations

    1

    h-index

  4. Cell Reports

    1 publications · 130 citations

    1

    h-index

  5. Oncotarget

    1 publications · 24 citations

    1

    h-index

1–5