Concepedia

Cofactor-dependent Epimerization

Cofactor-Dependent Epimerization is an enzymatic stereoisomerization process that belongs to the class of epimerization reactions and is distinguished by its strict dependence on a non-protein organic cofactor to facilitate the inversion of configuration at a specific chiral center within a biosynthetic pathway.

9

Publications

336

Citations

37

Authors

19

Institutions

Publications per year

2017–2026

1

Parents

Publications

9

Structure of the epimerization domain of tyrocidine synthetase A

Stefan A. Samel, Paul Czodrowski, Lars‐Oliver Essen · Acta Crystallographica Section D Biological Crystallography · 2014 · 59 citations

, , +17

Substrate Recognition and Selection by the Initiation Module PheATE of Gramicidin S Synthetase

Lusong Luo, Michael D. Burkart, Torsten Stachelhaus et al. · Journal of the American Chemical Society · 2001 · 54 citations

, , +15

Dimerization of Bacterial Diaminopimelate Epimerase Is Essential for Catalysis

Lilian Hor, Renwick C. J. Dobson, Matthew T. Downton et al. · Journal of Biological Chemistry · 2013 · 51 citations · Full text

, , +11

Involvement of 3-dehydroecdysone in the 3-epimerization of ecdysone

N P Milner, Huw H. Rees · Biochemical Journal · 1985 · 47 citations · Full text

, , +12

Molecular basis of Celmer’s rules: role of the ketosynthase domain in epimerisation and demonstration that ketoreductase domains can have altered product specificity with unnatural substrates

Inès E. Holzbaur, Anand Ranganathan, Iain P Thomas et al. · Chemistry & Biology · 2001 · 45 citations · Full text

, , +16

1–5 of 9

Authors

37

  1. LH
    Lilian Hor

    La Trobe University, Australia

    1 publications · 51 citations

    1

    h-index

  2. NP
    N P Milner

    University of Liverpool, United Kingdom

    1 publications · 47 citations

    1

    h-index

  3. DE
    David E. Cane

    Brown University, United States

    1 publications · 29 citations

    1

    h-index

  4. SA
    Stefan A. Samel

    Philipps University of Marburg, Germany

    1 publications · 59 citations

    1

    h-index

  5. CA
    Craig A. Hutton

    The University of Melbourne, Australia

    1 publications · 51 citations

    1

    h-index

1–5 of 37

Institutions

19

  1. University of Liverpool

    Liverpool, United Kingdom

    1 h-index

    2 publications

    94 citations

  2. Oregon State University

    Corvallis, United States

    1 h-index

    3 publications

    72 citations

  3. CEA Grenoble

    Grenoble, France

    1 h-index

    3 publications

    39 citations

  4. Stanford University

    Stanford, United States

    1 h-index

    1 publications

    29 citations

  5. Merck KGaA, Darmstadt (Germany)

    Darmstadt, Germany

    1 h-index

    1 publications

    59 citations

  6. Shanghai Jiao Tong University

    Shanghai, China

    1 h-index

    4 publications

    96 citations

  7. Melbourne Bioinformatics

    Melbourne, Australia

    1 h-index

    2 publications

    102 citations

  8. Harvard University

    Cambridge, United States

    1 h-index

    4 publications

    216 citations

1–8 of 19

Venues

  1. Journal of the American Chemical Society

    JACS · 2 publications · 83 citations

    2

    h-index

  2. Chemistry & Biology

    2 publications · 69 citations

    2

    h-index

  3. Journal of Biological Chemistry

    JBC · 1 publications · 51 citations

    1

    h-index

  4. 1

    h-index

  5. Biochimie

    1 publications · 13 citations

    1

    h-index

1–5