Concepedia

Cofactor Binding Affinity

Cofactor Binding Affinity is a biochemical property that quantifies the strength of the non-covalent interaction between a specific cofactor and its target enzyme, distinguishing it from other molecular interactions by its functional dependence on catalytic activity enhancement.

210

Publications

10.5K

Citations

984

Authors

355

Institutions

Publications per year

2017–2026

26

Parents

Publications

210

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.

N L Esmon, Whyte G. Owen, Charles T. Esmon · Journal of Biological Chemistry · 1982 · 707 citations · Full text

, , +14

Mechanism of Triclosan Inhibition of Bacterial Fatty Acid Synthesis

Richard J. Heath, John R. Rubin, Debra R. Holland et al. · Journal of Biological Chemistry · 1999 · 547 citations · Full text

, , +15

Cofactor Binding Evokes Latent Differences in DNA Binding Specificity between Hox Proteins

Matthew Slattery, Todd Riley, Peng Liu et al. · Cell · 2011 · 538 citations · Full text

, , +17

Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

Scott H. Soderling, Sharon J. Bayuga, Joseph A. Beavo · Proceedings of the National Academy of Sciences · 1999 · 381 citations

, , +13

Molecular Characterization of New Selective Peroxisome Proliferator–Activated Receptor γ Modulators With Angiotensin Receptor Blocking Activity

Michael Schupp, Markus Clemenz, Romain Gineste et al. · Diabetes · 2005 · 268 citations · Full text

, , +17

1–5 of 210

Authors

984

  1. PJ
    Philip J. Fay

    University of Rochester, United States

    7 publications · 286 citations

    7

    h-index

  2. HW
    Hironao Wakabayashi

    University of Rochester, United States

    5 publications · 228 citations

    5

    h-index

  3. GH
    Gerhard Hübner

    Martin Luther University Halle-Wittenberg, Germany

    4 publications · 91 citations

    4

    h-index

  4. WR
    Wolfram Ruf

    Scripps Research Institute, United States

    4 publications · 173 citations

    4

    h-index

  5. JA
    Jules A. Shafer

    University of Michigan, United States

    4 publications · 124 citations

    4

    h-index

1–5 of 984

Institutions

355

  1. University of Rochester

    Rochester, United States

    7 h-index

    27 publications

    1.1K citations

  2. University of Wisconsin–Madison

    Madison, United States

    7 h-index

    27 publications

    1.2K citations

  3. Scripps Research Institute

    San Diego, United States

    6 h-index

    14 publications

    962 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    23 publications

    607 citations

  5. National Institutes of Health

    Bethesda, United States

    5 h-index

    16 publications

    586 citations

  6. University of Michigan

    Ann Arbor, United States

    5 h-index

    14 publications

    650 citations

  7. Lund University

    Lund, Sweden

    4 h-index

    11 publications

    240 citations

  8. University of Würzburg

    Würzburg, Germany

    4 h-index

    24 publications

    666 citations

1–8 of 355

Venues

  1. Journal of Biological Chemistry

    JBC · 30 publications · 2.3K citations

    22

    h-index

  2. Biochemistry

    36 publications · 1.2K citations

    21

    h-index

  3. Journal of the American Chemical Society

    JACS · 8 publications · 393 citations

    8

    h-index

  4. Biochemical Journal

    BJ · 6 publications · 317 citations

    6

    h-index

  5. Protein Science

    PS · 6 publications · 257 citations

    6

    h-index

1–5