Concepedia

Closed State Transitions

Closed State Transitions is a biophysical model that describes the conformational changes among non-conducting states of potassium channels prior to pore opening, distinguishing it from activation or inactivation transitions by specifically characterizing the sequential rearrangements within the closed-state ensemble that govern channel gating kinetics.

287

Publications

17.1K

Citations

1.2K

Authors

428

Institutions

Publications per year

2017–2026

66

Parents

Publications

287

Dynamic Rearrangement of the Outer Mouth of a K+ Channel during Gating

Yi Liu, Mark E. Jurman, Gary Yellen · Neuron · 1996 · 445 citations · Full text

, , +15

Gating and regulation of connexin 43 (Cx43) hemichannels

Jorge E. Contreras, Juan C. Sáez, Feliksas F. Bukauskas et al. · Proceedings of the National Academy of Sciences · 2003 · 442 citations · Full text

, , +17

Molecular Dynamics of the KcsA K+ Channel in a Bilayer Membrane

Simon Bernèche · Biophysical Journal · 2000 · 333 citations · Full text

, , +16

Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels

Eduardo Perozo, Roderick MacKinnon, Francisco Bezanilla et al. · Neuron · 1993 · 325 citations

, , +14

A Hydrophobic Gating Mechanism for Nanopores

Oliver Beckstein, Philip C. Biggin, Mark S.P. Sansom · The Journal of Physical Chemistry B · 2001 · 298 citations

, , +16

1–5 of 287

Authors

1.2K

  1. MW
    Mir Wais Hosseini

    Centre National de la Recherche Scientifique, France

    6 publications · 145 citations

    6

    h-index

  2. NK
    Nathalie Kyritsakas

    Centre National de la Recherche Scientifique, France

    6 publications · 145 citations

    6

    h-index

  3. EG
    Ernest Graf

    Centre National de la Recherche Scientifique, France

    4 publications · 117 citations

    4

    h-index

  4. RB
    Roland Benz

    University of Würzburg, Germany

    4 publications · 307 citations

    4

    h-index

  5. PP
    Paola Picotti

    ETH Zurich, Switzerland

    3 publications · 75 citations

    3

    h-index

1–5 of 1.2K

Institutions

428

  1. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    81 publications

    4.2K citations

  2. Chinese Academy of Sciences

    Beijing, China

    10 h-index

    45 publications

    2.8K citations

  3. National Institutes of Health

    Bethesda, United States

    9 h-index

    25 publications

    1.6K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    8 h-index

    24 publications

    2.2K citations

  5. University of Chinese Academy of Sciences

    Beijing, China

    7 h-index

    27 publications

    1.2K citations

  6. Harvard University

    Cambridge, United States

    7 h-index

    21 publications

    3K citations

  7. University of California, Los Angeles

    Los Angeles, United States

    6 h-index

    18 publications

    632 citations

  8. Université de Strasbourg

    Strasbourg, France

    6 h-index

    24 publications

    553 citations

1–8 of 428

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 22 publications · 2.3K citations

    21

    h-index

  2. Journal of Biological Chemistry

    JBC · 20 publications · 808 citations

    17

    h-index

  3. The Journal of General Physiology

    JGP · 16 publications · 1.1K citations

    16

    h-index

  4. Biochemistry

    14 publications · 510 citations

    12

    h-index

  5. The Journal of Physiology

    13 publications · 1K citations

    11

    h-index

1–5