Juan C. Sáez

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.

Juan C. Sáez, John A. Connor, David C. Spray et al. · Proceedings of the National Academy of Sciences · 1989 · 593 citations · Full text

Second Messenger, Molecular Biology, Cell Junctions +23

Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

Jorge E. Contreras, Helmut A. Sánchez, Eliseo A. Eugenín et al. · Proceedings of the National Academy of Sciences · 2001 · 535 citations · Full text

Unapposed Connexin 43, Junctional Communication, Neurotransmission +22

Cx43 Hemichannels and Gap Junction Channels in Astrocytes Are Regulated Oppositely by Proinflammatory Cytokines Released from Activated Microglia

Mauricio A. Retamal, Nicolas Froger, Nicolás Palacios‐Prado et al. · Journal of Neuroscience · 2007 · 472 citations · Full text

Gating and regulation of connexin 43 (Cx43) hemichannels

Jorge E. Contreras, Juan C. Sáez, Feliksas F. Bukauskas et al. · Proceedings of the National Academy of Sciences · 2003 · 437 citations · Full text

ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

Juan Orellana, Nicolas Froger, Pascal Ezan et al. · Journal of Neurochemistry · 2011 · 371 citations · Full text

H Hypoxia, Immunology, Receptor Antagonist +22