Juan C. Sáez

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.

Juan C. Sáez, John A. Connor, David C. Spray et al. · Proceedings of the National Academy of Sciences · 1989 · 594 citations · Full text

Life Sciences, Cell Biology, Physiology +17

Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

Jorge E. Contreras, Helmut A. Sánchez, Eliseo A. Eugenín et al. · Proceedings of the National Academy of Sciences · 2001 · 543 citations · Full text

Life Sciences, Cell Biology, Neuroscience +14

Cx43 Hemichannels and Gap Junction Channels in Astrocytes Are Regulated Oppositely by Proinflammatory Cytokines Released from Activated Microglia

Mauricio A. Retamal, Nicolas Froger, Nicolás Palacios‐Prado et al. · Journal of Neuroscience · 2007 · 484 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Gating and regulation of connexin 43 (Cx43) hemichannels

Jorge E. Contreras, Juan C. Sáez, Feliksas F. Bukauskas et al. · Proceedings of the National Academy of Sciences · 2003 · 442 citations · Full text

Life Sciences, Biophysics, Cell Biology +17

ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

Juan Orellana, Nicolas Froger, Pascal Ezan et al. · Journal of Neurochemistry · 2011 · 376 citations · Full text

Medicine, Cell Biology, Neurobiology +17