Concepedia

Clamp Closing

Clamp Closing is a molecular mechanism in DNA replication that refers to the process by which a sliding clamp protein encircles duplex DNA through the closure of an otherwise topologically open ring structure, thereby enabling processive engagement with DNA polymerase.

25

Publications

870

Citations

127

Authors

49

Institutions

Publications per year

2017–2026

6

Parents

Publications

25

A Novel Mechanism of Cell Killing by Anti-topoisomerase II Bisdioxopiperazines

Lars H. Jensen, Karin C. Nitiss, Angela Rose et al. · Journal of Biological Chemistry · 2000 · 96 citations · Full text

, , +13

Molecular Structures of Transcribing RNA Polymerase I

Lucas Tafur, Yashar Sadian, N. Hoffmann et al. · Molecular Cell · 2016 · 95 citations · Full text

, , +17

MukB acts as a macromolecular clamp in DNA condensation

Yuanbo Cui, Zoya M. Petrushenko, Valentin V. Rybenkov · Nature Structural & Molecular Biology · 2008 · 88 citations

, , +12

Mechanism of β Clamp Opening by the δ Subunit ofEscherichia coli DNA Polymerase III Holoenzyme

Jelena Stewart, Manju Hingorani, Zvi Kelman et al. · Journal of Biological Chemistry · 2001 · 69 citations · Full text

, , +17

Mechanistic behavior and subtle key events during DNA clamp opening and closing in T4 bacteriophage

Vijay Kumar Bhardwaj, Aaron J. Oakley, Rituraj Purohit · International Journal of Biological Macromolecules · 2022 · 69 citations · Full text

, , +17

1–5 of 25

Authors

127

  1. AH
    Anni H. Andersen

    Aarhus University, Denmark

    3 publications · 96 citations

    3

    h-index

  2. SJ
    Stephen J. Benkovic

    Pennsylvania State University, United States

    3 publications · 93 citations

    3

    h-index

  3. LH
    Lars H. Jensen

    Rigshospitalet, Denmark

    2 publications · 119 citations

    2

    h-index

  4. VH
    Vibe H. Oestergaard

    University of Copenhagen, Denmark

    2 publications · 49 citations

    2

    h-index

  5. BR
    Birgitta R. Knudsen

    Aarhus University, Denmark

    2 publications · 49 citations

    2

    h-index

1–5 of 127

Institutions

49

  1. Pennsylvania State University

    State College, United States

    3 h-index

    14 publications

    344 citations

  2. St. Jude Children's Research Hospital

    Memphis, United States

    3 h-index

    12 publications

    681 citations

  3. Vanderbilt University

    Nashville, United States

    2 h-index

    7 publications

    378 citations

  4. Rigshospitalet

    Copenhagen, Denmark

    2 h-index

    8 publications

    403 citations

  5. University of Wollongong

    Wollongong, Australia

    2 h-index

    3 publications

    97 citations

  6. Aarhus University

    Aarhus, Denmark

    2 h-index

    8 publications

    207 citations

  7. Duke University

    Durham, United States

    2 h-index

    2 publications

    119 citations

  8. China Construction Eighth Engineering Division (China)

    Pudong, China

    1 h-index

    1 publications

    14 citations

1–8 of 49

Venues

  1. Journal of Biological Chemistry

    JBC · 8 publications · 314 citations

    8

    h-index

  2. Biochemistry

    3 publications · 104 citations

    3

    h-index

  3. Nucleic Acids Research

    2 publications · 31 citations

    2

    h-index

  4. Molecular Cell

    1 publications · 95 citations

    1

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 13 citations

    1

    h-index

1–5