Concepedia

Chromodomain Targeting

Chromodomain Targeting is a molecular recognition mechanism in chemical epigenetics that specifically directs effector proteins or synthetic ligands to modified histone tails through selective binding of chromatin-associated chromodomains to methylated lysine residues.

21

Publications

1.6K

Citations

154

Authors

54

Institutions

Publications per year

2017–2026

6

Parents

Publications

21

A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1

Jacob I. Stuckey, Bradley M. Dickson, Nancy Cheng et al. · Nature Chemical Biology · 2016 · 229 citations

, , +14

Chromodomains direct integration of retrotransposons to heterochromatin

Xiang Gao, Yi Hou, Hirotaka Ebina et al. · Genome Research · 2008 · 218 citations · Full text

, , +16

A Chromodomain Protein Encoded by the Arabidopsis <i>CAO</i> Gene Is a Plant-Specific Component of the Chloroplast Signal Recognition Particle Pathway That Is Involved in LHCP Targeting

Victor I. Klimyuk, Fabienne Cartieaux, Michel Havaux et al. · The Plant Cell · 1999 · 160 citations · Full text

, , +17

Specificity of the Chromodomain Y Chromosome Family of Chromodomains for Lysine-methylated ARK(S/T) Motifs

Wolfgang Fischle, Henriette Franz, Steven Jacobs et al. · Journal of Biological Chemistry · 2008 · 129 citations · Full text

, , +9

Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain

Chunyan Ren, Keita Morohashi, A.N. Plotnikov et al. · Chemistry & Biology · 2015 · 129 citations · Full text

, , +15

1–5 of 21

Authors

154

  1. ML
    Marcey L. Waters

    University of North Carolina at Chapel Hill, United States

    4 publications · 151 citations

    4

    h-index

  2. LI
    Lindsey I. James

    University of North Carolina at Chapel Hill, United States

    3 publications · 270 citations

    3

    h-index

  3. FH
    Fraser Hof

    University of Victoria, Canada

    3 publications · 246 citations

    3

    h-index

  4. YL
    Yanli Liu

    Soochow University, China

    3 publications · 311 citations

    3

    h-index

  5. JM
    Jinrong Min

    University of Toronto, Canada

    3 publications · 311 citations

    3

    h-index

1–5 of 154

Institutions

54

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    6 h-index

    43 publications

    3.6K citations

  2. University of Victoria

    Victoria, Canada

    3 h-index

    28 publications

    2.2K citations

  3. University of Toronto

    Toronto, Canada

    2 h-index

    17 publications

    2.6K citations

  4. Structural Genomics Consortium

    Toronto, Canada

    2 h-index

    17 publications

    2.6K citations

  5. Central China Normal University

    Wuhan, China

    2 h-index

    6 publications

    190 citations

  6. Rockefeller University

    New York, United States

    1 h-index

    2 publications

    258 citations

  7. Heinrich Heine University Düsseldorf

    Düsseldorf, Germany

    1 h-index

    1 publications

    160 citations

  8. Centrum Wiskunde & Informatica

    Amsterdam, The Netherlands

    1 h-index

    1 publications

    14 citations

1–8 of 54

Venues

  1. ACS Chemical Biology

    3 publications · 133 citations

    3

    h-index

  2. Journal of Medicinal Chemistry

    2 publications · 128 citations

    2

    h-index

  3. Journal of Biological Chemistry

    JBC · 2 publications · 142 citations

    2

    h-index

  4. Nature Structural & Molecular Biology

    2 publications · 166 citations

    2

    h-index

  5. Nature Communications

    1 publications · 17 citations

    1

    h-index

1–5