Concepedia

Chromatin Insulators

Chromatin Insulators is a DNA-protein complex that functions as a cis-regulatory element distinguished by its ability to block enhancer-promoter interactions and prevent the spread of heterochromatin, thereby maintaining independent regulatory domains within the chromatin architecture.

160

Publications

14.7K

Citations

670

Authors

238

Institutions

Publications per year

2017–2026

19

Parents

Publications

160

The Protein CTCF Is Required for the Enhancer Blocking Activity of Vertebrate Insulators

Adam C. Bell, Adam G. West, Gary Felsenfeld · Cell · 1999 · 1.1K citations · Full text

, , +15

Analysis of the Vertebrate Insulator Protein CTCF-Binding Sites in the Human Genome

Tae Hoon Kim, Ziedulla Abdullaev, Andrew D. Smith et al. · Cell · 2007 · 1.1K citations · Full text

, , +14

Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

Suresh Cuddapah, Raja Jothi, Dustin E. Schones et al. · Genome Research · 2008 · 644 citations · Full text

, , +17

Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators

Michael J. Pikaart, Félix Recillas‐Targa, Gary Felsenfeld · Genes & Development · 1998 · 399 citations · Full text

, , +17

Characterization of the chicken β-globin insulator

Jay H. Chung, Adam C. Bell, Gary Felsenfeld · Proceedings of the National Academy of Sciences · 1997 · 391 citations

, , +17

1–5 of 160

Authors

670

  1. PG
    Pavel Georgiev

    Institute of Gene Biology, Russia

    16 publications · 998 citations

    15

    h-index

  2. VG
    Victor G. Corces

    Johns Hopkins University, United States

    13 publications · 1.9K citations

    13

    h-index

  3. EP
    Elissa P. Lei

    National Institute of Diabetes and Digestive and Kidney Diseases, United States

    8 publications · 598 citations

    8

    h-index

  4. LS
    L. S. Melnikova

    Institute of Gene Biology, Russia

    6 publications · 187 citations

    6

    h-index

  5. RD
    Ryan Dale

    National Institutes of Health, United States

    6 publications · 320 citations

    6

    h-index

1–5 of 670

Institutions

238

  1. National Institutes of Health

    Bethesda, United States

    17 h-index

    64 publications

    13.3K citations

  2. Institute of Gene Biology

    Moscow, Russia

    16 h-index

    69 publications

    5.2K citations

  3. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    14 h-index

    55 publications

    9.4K citations

  4. Johns Hopkins University

    Baltimore, United States

    12 h-index

    30 publications

    4.9K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    35 publications

    2.7K citations

  6. Harvard University

    Cambridge, United States

    6 h-index

    18 publications

    2.7K citations

  7. University of Washington Medical Center

    Seattle, United States

    6 h-index

    17 publications

    1.3K citations

  8. University of Georgia

    Athens, United States

    6 h-index

    18 publications

    787 citations

1–8 of 238

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 988 citations

    11

    h-index

  2. Nucleic Acids Research

    11 publications · 487 citations

    11

    h-index

  3. Molecular and Cellular Biology

    MCB · 9 publications · 531 citations

    9

    h-index

  4. Genetics

    7 publications · 284 citations

    7

    h-index

  5. Development

    7 publications · 414 citations

    7

    h-index

1–5