Concepedia

Chromatin Fragmentation

Chromatin Fragmentation is a biochemical process characterized by the cleavage of nuclear chromatin into oligonucleosomal-sized fragments, serving as a hallmark morphological change during apoptosis resulting from the activation of specific endonucleases.

390

Publications

41.9K

Citations

1.5K

Authors

519

Institutions

Publications per year

2017–2026

32

Parents

Publications

390

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology · 1992 · 9.5K citations · Full text

, , +13

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

A H Wyllie, R. G. Morris, Alex Smith et al. · The Journal of Pathology · 1984 · 1.6K citations

, , +16

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

John Cohen, Richard C. Duke · The Journal of Immunology · 1984 · 1.4K citations

, , +16

Two Distinct Pathways Leading to Nuclear Apoptosis

Santos A. Susín, Éric Daugas, L Ravagnan et al. · The Journal of Experimental Medicine · 2000 · 735 citations · Full text

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Initiation of DNA Fragmentation during Apoptosis Induces Phosphorylation of H2AX Histone at Serine 139

Emmy P. Rogakou, Wilberto Nieves‐Neira, Chye Boon et al. · Journal of Biological Chemistry · 2000 · 714 citations · Full text

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1–5 of 390

Authors

1.5K

  1. WS
    W. Steven Ward

    University of Hawaiʻi at Mānoa, United States

    9 publications · 490 citations

    9

    h-index

  2. WT
    William T. Garrard

    The University of Texas Southwestern Medical Center, United States

    7 publications · 1K citations

    7

    h-index

  3. SO
    Sten Orrenius

    Karolinska Institutet, Sweden

    6 publications · 1.4K citations

    6

    h-index

  4. HG
    Hans Georg Mannherz

    Ruhr University Bochum, Germany

    6 publications · 899 citations

    6

    h-index

  5. DD
    Detlef Doenecke

    University of Göttingen, Germany

    6 publications · 172 citations

    6

    h-index

1–5 of 1.5K

Institutions

519

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    11 h-index

    37 publications

    7.3K citations

  2. University of Hawaiʻi at Mānoa

    Honolulu, United States

    10 h-index

    40 publications

    2.1K citations

  3. MRC Toxicology Unit

    Cambridge, United Kingdom

    7 h-index

    25 publications

    6.3K citations

  4. Tokyo University of Science

    Tokyo, Japan

    7 h-index

    25 publications

    901 citations

  5. University of Leicester

    Leicester, United Kingdom

    6 h-index

    24 publications

    2K citations

  6. Karolinska Institutet

    Stockholm, Sweden

    6 h-index

    28 publications

    5.7K citations

  7. Kyoto University

    Kyoto, Japan

    6 h-index

    26 publications

    1.4K citations

  8. University of Debrecen

    Debrecen, Hungary

    6 h-index

    22 publications

    372 citations

1–8 of 519

Venues

  1. Journal of Biological Chemistry

    JBC · 27 publications · 3.7K citations

    24

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  2. PubMed

    Repository · 23 publications · 1.4K citations

    15

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 2.2K citations

    11

    h-index

  4. FEBS Letters

    11 publications · 737 citations

    11

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 10 publications · 225 citations

    10

    h-index

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