Concepedia

Cholangiocyte Differentiation

Cholangiocyte Differentiation is a developmental biological process in which hepatoblasts commit to and mature into cholangiocytes, the specialized epithelial cells lining the biliary ducts of the liver, through spatially and temporally regulated signaling pathways and transcriptional programs distinct from hepatocyte lineage specification.

259

Publications

20.2K

Citations

1.8K

Authors

507

Institutions

Publications per year

2017–2026

90

Parents

Publications

259

Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration

Alexander Raven, Wei‐Yu Lu, Tak Yung Man et al. · Nature · 2017 · 532 citations · Full text

, , +16

Robust cellular reprogramming occurs spontaneously during liver regeneration

Kilangsungla Yanger, Yiwei Zong, Lara R. Maggs et al. · Genes & Development · 2013 · 501 citations · Full text

, , +17

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

Supriya K. Saha, Christine A. Parachoniak, Krishna S. Ghanta et al. · Nature · 2014 · 469 citations

, , +14

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

Fotios Sampaziotis, Miguel Cardoso de Brito, Pedro Madrigal et al. · Nature Biotechnology · 2015 · 395 citations · Full text

, , +13

Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

Sayaka Sekiya, Atsushi Suzuki · Journal of Clinical Investigation · 2012 · 362 citations

, , +17

1–5 of 259

Authors

1.8K

  1. GA
    Gianfranco Alpini

    Central Texas Veterans Health Care System, United States

    12 publications · 1K citations

    12

    h-index

  2. EG
    Eugenio Gaudio

    Sapienza University of Rome, Italy

    8 publications · 561 citations

    8

    h-index

  3. NT
    Naoki Tanimizu

    Sapporo Medical University, Japan

    8 publications · 777 citations

    8

    h-index

  4. NJ
    Nidhi Jalan‐Sakrikar

    Mayo Clinic, United States

    6 publications · 344 citations

    6

    h-index

  5. RC
    Robert C. Huebert

    Mayo Clinic, United States

    6 publications · 344 citations

    6

    h-index

1–5 of 1.8K

Institutions

507

  1. University of Pittsburgh

    Pittsburgh, United States

    12 h-index

    52 publications

    4.5K citations

  2. The University of Tokyo

    Tokyo, Japan

    12 h-index

    60 publications

    5.5K citations

  3. Kanazawa University

    Kanazawa, Japan

    11 h-index

    38 publications

    2.9K citations

  4. Mayo Clinic

    Rochester, United States

    10 h-index

    65 publications

    4.7K citations

  5. Kyushu University

    Fukuoka, Japan

    10 h-index

    55 publications

    2.5K citations

  6. University of California, San Francisco

    San Francisco, United States

    8 h-index

    41 publications

    6.1K citations

  7. University of Pennsylvania

    Philadelphia, United States

    8 h-index

    18 publications

    4.8K citations

  8. Inserm

    Paris, France

    7 h-index

    35 publications

    4.5K citations

1–8 of 507

Venues

  1. Hepatology

    32 publications · 2.9K citations

    25

    h-index

  2. Journal of Hepatology

    19 publications · 1.4K citations

    18

    h-index

  3. PubMed

    Repository · 17 publications · 1K citations

    15

    h-index

  4. American Journal Of Pathology

    AJP · 12 publications · 681 citations

    12

    h-index

  5. Laboratory Investigation

    12 publications · 905 citations

    12

    h-index

1–5