Concepedia

Checkpoint Blockade Regulation

Checkpoint Blockade Regulation is a molecular immunotherapeutic strategy that belongs to the class of immune checkpoint interventions, distinguished by its specific inhibition of inhibitory signaling pathways in T cells to enhance antitumor immune responses.

37

Publications

4.1K

Citations

418

Authors

150

Institutions

Publications per year

2017–2026

34

Parents

Publications

37

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

Wanqiang Sheng, Martin W. LaFleur, Thao H. Nguyen et al. · Cell · 2018 · 679 citations

, , +14

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice R. Gurbatri, Ioana Lia, Rosa L. Vincent et al. · Science Translational Medicine · 2020 · 596 citations · Full text

, , +17

Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade

Xiaoming Dai, Xia Bu, Yang Gao et al. · Molecular Cell · 2021 · 248 citations · Full text

, , +17

Immune Checkpoint Blockade in Cancer Therapy: The 2015 Lasker-DeBakey Clinical Medical Research Award.

James P. Allison · PubMed · 2015 · 208 citations

, , +17

The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response

Merav Cohen, Amir Giladi, Oren Barboy et al. · Nature Cancer · 2022 · 196 citations

, , +17

1–5 of 37

Authors

418

  1. NA
    Nicholas Arpaia

    Columbia University Irving Medical Center, United States

    2 publications · 635 citations

    2

    h-index

  2. IL
    Ioana Lia

    Columbia University, United States

    2 publications · 635 citations

    2

    h-index

  3. CR
    Candice R. Gurbatri

    Columbia University, United States

    2 publications · 635 citations

    2

    h-index

  4. TD
    Tal Danino

    Columbia University, United States

    2 publications · 635 citations

    2

    h-index

  5. TE
    Taylor E. Hinchliffe

    Columbia University, United States

    2 publications · 635 citations

    2

    h-index

1–5 of 418

Institutions

150

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    9 publications

    415 citations

  2. Istituti di Ricovero e Cura a Carattere Scientifico

    Rome, Italy

    3 h-index

    28 publications

    1.1K citations

  3. Princess Margaret Cancer Centre

    Toronto, Canada

    3 h-index

    8 publications

    3.2K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    3 h-index

    3 publications

    457 citations

  5. Central South University

    Changsha, China

    2 h-index

    27 publications

    3.2K citations

  6. Columbia University

    New York, United States

    2 h-index

    15 publications

    5K citations

  7. State Key Laboratory of Oncogene and Related Genes

    Shanghai, China

    2 h-index

    4 publications

    408 citations

  8. Brigham and Women's Hospital

    Boston, United States

    2 h-index

    3 publications

    1.2K citations

1–8 of 150

Venues

  1. Nature Communications

    3 publications · 200 citations

    3

    h-index

  2. Frontiers in Oncology

    2 publications · 75 citations

    2

    h-index

  3. Molecular Cell

    1 publications · 248 citations

    1

    h-index

  4. Cell Reports

    1 publications · 34 citations

    1

    h-index

  5. Journal for ImmunoTherapy of Cancer

    JITC · 1 publications · 86 citations

    1

    h-index

1–5