Concepedia

Chaperone Coexpression

Chaperone Coexpression is a recombinant antibody expression technique that involves the concurrent expression of molecular chaperones alongside antibody chains to enhance proper folding, assembly, and solubility of recombinant antibodies in heterologous host systems.

51

Publications

2.8K

Citations

281

Authors

122

Institutions

Publications per year

2017–2026

10

Parents

Publications

51

Chaperone Coexpression Plasmids: Differential and Synergistic Roles of DnaK-DnaJ-GrpE and GroEL-GroES in Assisting Folding of an Allergen of Japanese Cedar Pollen, Cryj2, in <i>Escherichia coli</i>

Kazuyo Nishihara, Masaaki Kanemori, Masanari Kitagawa et al. · Applied and Environmental Microbiology · 1998 · 432 citations · Full text

, , +17

Production of Correctly Folded Fab Antibody Fragment in the Cytoplasm of Escherichia coli trxB gor Mutants via the Coexpression of Molecular Chaperones

Robert B. Weiss, Gang Chen, Brent L. Iverson et al. · Protein Expression and Purification · 2001 · 205 citations

, , +17

Cooverexpression of chaperones for enhanced secretion of a single-chain antibody fragment in Pichia pastoris

Leonardo M. Damasceno, Kyle A. Anderson, Gerd Ritter et al. · Applied Microbiology and Biotechnology · 2006 · 166 citations

, , +16

Heterologous Production of Epothilone C and D in <i>Escherichia coli</i>

Sarah C. Mutka, John R. Carney, Yaoquan Liu et al. · Biochemistry · 2006 · 154 citations

, , +17

Escherichia coliSkp Chaperone Coexpression Improves Solubility and Phage Display of Single-Chain Antibody Fragments

Andrew Hayhurst, William J. Harris · Protein Expression and Purification · 1999 · 134 citations

, , +14

1–5 of 51

Authors

281

  1. MJ
    Michael J. Betenbaugh

    Johns Hopkins University, United States

    3 publications · 110 citations

    3

    h-index

  2. CG
    Charles Grose

    University of Iowa, United States

    2 publications · 69 citations

    2

    h-index

  3. EM
    Erik M. Whiteley

    Johns Hopkins University, United States

    2 publications · 40 citations

    2

    h-index

  4. TH
    Tsu‐An Hsu

    National Health Research Institutes, Taiwan

    2 publications · 40 citations

    2

    h-index

  5. EA
    Eric Ailor

    Johns Hopkins University, United States

    2 publications · 88 citations

    2

    h-index

1–5 of 281

Institutions

122

  1. Johns Hopkins University

    Baltimore, United States

    3 h-index

    10 publications

    296 citations

  2. The University of Osaka

    Osaka, Japan

    2 h-index

    4 publications

    146 citations

  3. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    6 publications

    316 citations

  4. University of Edinburgh

    Edinburgh, United Kingdom

    2 h-index

    3 publications

    227 citations

  5. Johns Hopkins Medicine

    Baltimore, United States

    2 h-index

    7 publications

    134 citations

  6. Daiichi-Sankyo (Japan)

    Tokyo, Japan

    2 h-index

    9 publications

    237 citations

  7. University of Kent

    Canterbury, United Kingdom

    1 h-index

    3 publications

    33 citations

  8. University Medical Center Freiburg

    Freiburg im Breisgau, Germany

    1 h-index

    1 publications

    92 citations

1–8 of 122

Venues

  1. Protein Expression and Purification

    5 publications · 449 citations

    5

    h-index

  2. Applied Microbiology and Biotechnology

    4 publications · 274 citations

    4

    h-index

  3. Biotechnology Progress

    3 publications · 80 citations

    3

    h-index

  4. Biotechnology and Bioengineering

    3 publications · 123 citations

    3

    h-index

  5. Applied and Environmental Microbiology

    AEM · 3 publications · 491 citations

    3

    h-index

1–5