Concepedia

Centromere Engineering

Centromere Engineering is a specialized methodological approach within chromosome engineering that involves the precise modification or de novo design of centromeric DNA sequences and associated epigenetic structures to alter chromosome segregation behavior, stability, or inheritance patterns in eukaryotic cells.

14

Publications

1.7K

Citations

173

Authors

32

Institutions

Publications per year

2017–2026

5

Parents

Publications

14

Isolation of a yeast centromere and construction of functional small circular chromosomes

Louise Clarke, John Carbon · Nature · 1980 · 803 citations

, , +14

Genetic manipulation of centromere function.

Alison Hill, Kerry Bloom · Molecular and Cellular Biology · 1987 · 209 citations · Full text

, , +17

Genetic Manipulation of Centromere function

Alison Hill, Kerry Bloom · Molecular and Cellular Biology · 1987 · 128 citations

, , +17

Human Artificial Chromosomes that Bypass Centromeric DNA

Glennis A. Logsdon, Craig W. Gambogi, Mikhail Liskovykh et al. · Cell · 2019 · 106 citations · Full text

, , +14

Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells

Jung-Hyun Kim, Artem V. Kononenko, Indri Erliandri et al. · Proceedings of the National Academy of Sciences · 2011 · 79 citations · Full text

, , +17

1–5 of 14

Authors

173

  1. BE
    Ben E. Black

    University of Pennsylvania, United States

    2 publications · 137 citations

    2

    h-index

  2. PH
    Patrick Heun

    Wellcome Centre for Cell Biology, United Kingdom

    2 publications · 137 citations

    2

    h-index

  3. GA
    Glennis A. Logsdon

    University of Washington, United States

    2 publications · 137 citations

    2

    h-index

  4. YI
    Yuichi Iida

    Shimane University, Japan

    2 publications · 147 citations

    2

    h-index

  5. NK
    Natalay Kouprina

    National Cancer Institute, United States

    2 publications · 147 citations

    2

    h-index

1–5 of 173

Institutions

32

  1. University of Edinburgh

    Edinburgh, United Kingdom

    5 h-index

    10 publications

    525 citations

  2. Wellcome Centre for Cell Biology

    Edinburgh, United Kingdom

    4 h-index

    6 publications

    421 citations

  3. National Cancer Institute

    Bethesda, United States

    3 h-index

    9 publications

    710 citations

  4. Kazusa DNA Research Institute

    Kisarazu, Japan

    2 h-index

    4 publications

    305 citations

  5. Tottori University

    Tottori-shi, Japan

    2 h-index

    8 publications

    566 citations

  6. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    11 publications

    566 citations

  7. Institute for Systems Biology

    Seattle, United States

    2 h-index

    40 publications

    2K citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    3 publications

    465 citations

1–8 of 32

Venues

  1. Cell

    2 publications · 176 citations

    2

    h-index

  2. Molecular and Cellular Biology

    MCB · 2 publications · 337 citations

    2

    h-index

  3. Cell Genomics

    1 publications · 26 citations

    1

    h-index

  4. Science

    1 publications · 31 citations

    1

    h-index

  5. PLoS ONE

    1 publications · 49 citations

    1

    h-index

1–5