Concepedia

Centromere Dysfunction

Centromere Dysfunction is a biological phenomenon characterized by the impaired functioning of the centromere, a specialized chromosomal region essential for proper kinetochore assembly and chromosome segregation, resulting in aberrant mitotic progression and contributing to chromosomal instability.

64

Publications

3.9K

Citations

301

Authors

136

Institutions

Publications per year

2017–2026

7

Parents

Publications

64

Human centromere repositioning “in progress”

David J. Amor, Karen Bentley, Jacinta Ryan et al. · Proceedings of the National Academy of Sciences · 2004 · 294 citations · Full text

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Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining

Peter Ly, Levi S. Teitz, Dong Hyun Kim et al. · Nature Cell Biology · 2016 · 288 citations · Full text

, , +17

Loss of pRB causes centromere dysfunction and chromosomal instability

Amity L. Manning, Michelle S. Longworth, Nicholas J. Dyson · Genes & Development · 2010 · 242 citations · Full text

, , +17

Heterochromatin Integrity Affects Chromosome Reorganization After Centromere Dysfunction

Kojiro Ishii, Yuki Ogiyama, Yuji Chikashige et al. · Science · 2008 · 206 citations

, , +17

Integration of human α-satellite DNA into simian chromosomes: Centromere protein binding and disruption of normal chromosome segregation

Thomas Haaf · Cell · 1992 · 183 citations

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1–5 of 64

Authors

301

  1. MF
    Molly Fitzgerald‐Hayes

    University of Massachusetts Amherst, United States

    3 publications · 261 citations

    3

    h-index

  2. TH
    Thomas Haaf

    University of Würzburg, Germany

    2 publications · 209 citations

    2

    h-index

  3. ND
    Ninoslav Djelić

    University of Belgrade, Serbia

    2 publications · 65 citations

    2

    h-index

  4. BS
    Biljana Spremo‐Potparević

    University of Belgrade, Serbia

    2 publications · 65 citations

    2

    h-index

  5. AJ
    Andrew J. Schroeder

    Harvard University, United States

    2 publications · 176 citations

    2

    h-index

1–5 of 301

Institutions

136

  1. University of California San Diego

    San Diego, United States

    4 h-index

    12 publications

    1.8K citations

  2. Ludwig Cancer Research

    New York, United States

    3 h-index

    9 publications

    1.7K citations

  3. Sapienza University of Rome

    Rome, Italy

    2 h-index

    8 publications

    225 citations

  4. Oncology Institute of Vojvodina

    Novi Sad, Serbia

    2 h-index

    2 publications

    65 citations

  5. University of Pavia

    Pavia, Italy

    2 h-index

    14 publications

    308 citations

  6. University of Massachusetts Amherst

    Amherst Center, United States

    2 h-index

    8 publications

    704 citations

  7. Lund University

    Lund, Sweden

    2 h-index

    6 publications

    137 citations

  8. Thomas Jefferson University

    Philadelphia, United States

    2 h-index

    2 publications

    43 citations

1–8 of 136

Venues

  1. Human Genetics

    9 publications · 455 citations

    9

    h-index

  2. Chromosoma

    4 publications · 132 citations

    4

    h-index

  3. Genetics

    3 publications · 53 citations

    3

    h-index

  4. Journal of Medical Genetics

    JMG · 3 publications · 63 citations

    3

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 458 citations

    3

    h-index

1–5