Concepedia

Cell State Deconvolution

Cell State Deconvolution is a computational method in single-cell genomics that resolves the dynamic, functional states of cells within heterogeneous tissue samples by disentangling transcriptional profiles from bulk omics data, distinguishing itself from broader cell-type deconvolution by focusing on transient, context-specific cellular phenotypes rather than stable lineage-based classifications.

40

Publications

3.2K

Citations

290

Authors

130

Institutions

Publications per year

2017–2026

35

Parents

Publications

40

Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis

Ting Xie, Yizhou Wang, Nan Deng et al. · Cell Reports · 2018 · 559 citations · Full text

, , +17

Deep learning–based cell composition analysis from tissue expression profiles

Kevin Menden, Sergio Oller Moreno, Anupriya Dalmia et al. · Science Advances · 2020 · 296 citations · Full text

, , +17

Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling

Lucas A. Salas, Ze Zhang, Devin C. Koestler et al. · Nature Communications · 2022 · 277 citations · Full text

, , +16

Colorectal Cancer Metastases in the Liver Establish Immunosuppressive Spatial Networking between Tumor-Associated <i>SPP1</i> + Macrophages and Fibroblasts

Anuja Sathe, Kaishu Mason, Susan M. Grimes et al. · Clinical Cancer Research · 2022 · 193 citations · Full text

, , +17

Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species

Genevieve Stein-O’Brien, Brian S. Clark, Thomas D. Sherman et al. · Cell Systems · 2019 · 186 citations · Full text

, , +9

1–5 of 40

Authors

290

  1. LA
    Loyal A. Goff

    Johns Hopkins University, United States

    3 publications · 214 citations

    3

    h-index

  2. RS
    Rachel Sealfon

    Princeton University, United States

    3 publications · 214 citations

    3

    h-index

  3. AM
    Annette M. Molinaro

    University of California, San Francisco, United States

    3 publications · 319 citations

    3

    h-index

  4. QH
    Qiwen Hu

    Harvard University, United States

    3 publications · 214 citations

    3

    h-index

  5. JK
    John K. Wiencke

    University of California, San Francisco, United States

    3 publications · 319 citations

    3

    h-index

1–5 of 290

Institutions

130

  1. University of California, San Francisco

    San Francisco, United States

    5 h-index

    13 publications

    1.1K citations

  2. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    9 publications

    959 citations

  3. Johns Hopkins University

    Baltimore, United States

    3 h-index

    13 publications

    2K citations

  4. Translational Therapeutics (United States)

    Arlington, United States

    3 h-index

    3 publications

    248 citations

  5. Dartmouth College

    Hanover, United States

    3 h-index

    11 publications

    995 citations

  6. University of Kansas Medical Center

    Kansas City, United States

    3 h-index

    3 publications

    319 citations

  7. Brown University

    Providence, United States

    3 h-index

    5 publications

    619 citations

  8. Neurological Surgery

    Rockville Centre, United States

    3 h-index

    8 publications

    938 citations

1–8 of 130

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 6 publications · 108 citations

    6

    h-index

  2. Nature Communications

    6 publications · 655 citations

    6

    h-index

  3. Cell Systems

    2 publications · 196 citations

    2

    h-index

  4. Cell Reports

    2 publications · 674 citations

    2

    h-index

  5. Annals of the Rheumatic Diseases

    ARD · 1 publications · 73 citations

    1

    h-index

1–5