Concepedia

Catalytic Splicing Steps

Catalytic Splicing Steps is a biochemical process that constitutes the sequence of phosphoryl transfer reactions mediated by the spliceosome, distinguishing it from auxiliary splicing events by directly facilitating the cleavage and ligation of pre-mRNA termini during nuclear mRNA maturation.

243

Publications

18.3K

Citations

698

Authors

244

Institutions

Publications per year

2017–2026

27

Parents

Publications

243

Protein Splicing Converts the Yeast <i>TFP1</i> Gene Product to the 69-kdDSubunit of the Vacuolar H <sup>+</sup> -Adenosine Triphosphatase

Patricia M. Kane, Carl T. Yamashiro, David F Wolczyk et al. · Science · 1990 · 501 citations

, , +14

Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

Kenneth P.K. Lee, Madhusudan Dey, Dante Neculai et al. · Cell · 2008 · 385 citations · Full text

, , +12

Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins

Stanley Chun-Wei Lee, Heidi Dvinge, Eun Hee Kim et al. · Nature Medicine · 2016 · 354 citations · Full text

, , +13

Mechanism of action of a yeast RNA ligase in tRNA splicing

Chris L. Greer, Craig L. Peebles, Peter Gegenheimer et al. · Cell · 1983 · 317 citations

, , +12

The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome

Patrizia Fabrizio, Julia Dannenberg, Prakash Dube et al. · Molecular Cell · 2009 · 305 citations · Full text

, , +16

1–5 of 243

Authors

698

  1. EM
    Eric M. Phizicky

    University of Rochester, United States

    14 publications · 986 citations

    14

    h-index

  2. JA
    John Abelson

    California Institute of Technology, United States

    14 publications · 1.2K citations

    13

    h-index

  3. SC
    Soo-Chen Cheng

    Institute of Molecular Biology, Academia Sinica, Taiwan

    9 publications · 485 citations

    9

    h-index

  4. BS
    Beate Schwer

    Cornell University, United States

    8 publications · 488 citations

    8

    h-index

  5. CL
    Chris L. Greer

    University of California, Irvine, United States

    8 publications · 575 citations

    8

    h-index

1–5 of 698

Institutions

244

  1. New England Biolabs (United States)

    Ipswich, United States

    14 h-index

    46 publications

    5.1K citations

  2. University of Rochester

    Rochester, United States

    14 h-index

    45 publications

    2.9K citations

  3. Max Planck Institute for Biophysical Chemistry

    Göttingen, Germany

    13 h-index

    95 publications

    15.1K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    37 publications

    2.5K citations

  5. University of California, San Francisco

    San Francisco, United States

    11 h-index

    29 publications

    1.3K citations

  6. Institute of Molecular Biology, Academia Sinica

    Taipei, Taiwan

    10 h-index

    34 publications

    1.8K citations

  7. Rockefeller University

    New York, United States

    10 h-index

    25 publications

    2.1K citations

  8. Cornell University

    Ithaca, United States

    9 h-index

    25 publications

    1.9K citations

1–8 of 244

Venues

  1. Journal of Biological Chemistry

    JBC · 28 publications · 1.8K citations

    25

    h-index

  2. RNA

    29 publications · 1.6K citations

    22

    h-index

  3. Molecular and Cellular Biology

    MCB · 25 publications · 1.3K citations

    20

    h-index

  4. Biochemistry

    15 publications · 642 citations

    14

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 833 citations

    12

    h-index

1–5