Concepedia

Caspase Cascade Amplification

Caspase Cascade Amplification is a biochemical mechanism within apoptotic signal transduction that refers to the sequential and self-reinforcing activation of caspase enzymes, in which initiator caspases cleave and activate effector caspases, which in turn cleave downstream substrates and amplify the apoptotic signal through proteolytic amplification loops.

32

Publications

2.4K

Citations

187

Authors

72

Institutions

Publications per year

2017–2026

4

Parents

Publications

32

Conversion of Bcl-2 to a Bax-like Death Effector by Caspases

Emily H. Cheng, David G. Kirsch, Rollie J. Clem et al. · Science · 1997 · 1.1K citations

, , +16

Fas/CD95/Apo-I activates the acidic sphingomyelinase via Caspases

Brigit Brenner, Klaus Ferlinz, Heike Grassmé et al. · Cell Death and Differentiation · 1998 · 127 citations

, , +12

Gelsolin in Complex with Phosphatidylinositol 4,5-Bisphosphate Inhibits Caspase-3 and -9 to Retard Apoptotic Progression

Toshifumi Azuma, Kirston Koths, Lisa A. Flanagan et al. · Journal of Biological Chemistry · 2000 · 112 citations · Full text

, , +16

Time Course of the Apoptotic Cascade and Effects of Caspase Inhibitors in Adult Rat Ventricular Cardiomyocytes

Keisuke Suzuki, Sawa Kostin, Veronika Person et al. · Journal of Molecular and Cellular Cardiology · 2001 · 97 citations

, , +11

Caspase activation and cytochrome<i>c</i>release during HL-60 cell apoptosis induced by a nitric oxide donor

Munehisa Yabuki, Ken‐Ichiro Tsutsui, Alan A. Horton et al. · Free Radical Research · 2000 · 72 citations

, , +17

1–5 of 32

Authors

187

  1. MA
    Manzoor Ahmad

    Sidney Kimmel Cancer Center, United States

    1 publications · 40 citations

    1

    h-index

  2. BQ
    Bin Qiao

    Hainan Medical University, China

    1 publications · 24 citations

    1

    h-index

  3. IS
    Ingo Schmitz

    Otto-von-Guericke-Universität Magdeburg, Germany

    1 publications · 38 citations

    1

    h-index

  4. UK
    Ursula Koppenhoefer

    University of Tübingen, Germany

    1 publications · 127 citations

    1

    h-index

  5. CG
    Cathleen Gonzales

    Princeton University, United States

    1 publications · 32 citations

    1

    h-index

1–5 of 187

Institutions

72

  1. Johns Hopkins University

    Baltimore, United States

    2 h-index

    9 publications

    8.9K citations

  2. Okayama University

    Okayama, Japan

    2 h-index

    9 publications

    354 citations

  3. University of Tübingen

    Tübingen, Germany

    2 h-index

    10 publications

    946 citations

  4. National Centre for Cell Science

    Pune, India

    2 h-index

    7 publications

    294 citations

  5. King Faisal Specialist Hospital & Research Centre

    Riyadh, Saudi Arabia

    1 h-index

    3 publications

    120 citations

  6. Medical University of Lodz

    Lodz, Poland

    1 h-index

    2 publications

    34 citations

  7. Assam University

    Silchar, India

    1 h-index

    2 publications

    24 citations

  8. Minnan Normal University

    Zhangzhou, China

    1 h-index

    1 publications

    43 citations

1–8 of 72

Venues

  1. Molecular and Cellular Biology

    MCB · 2 publications · 101 citations

    2

    h-index

  2. Journal of Biological Chemistry

    JBC · 2 publications · 170 citations

    2

    h-index

  3. Toxicology

    2 publications · 51 citations

    2

    h-index

  4. Brain Research

    2 publications · 62 citations

    2

    h-index

  5. European Journal of Pharmacology

    EJP · 2 publications · 79 citations

    2

    h-index

1–5