Alan A. Horton

Mechanism of apoptosis in HL-60 cells induced by n-3 and n-6 polyunsaturated fatty acids 1 1Abbreviations: AA, arachidonic acid; CsA, cyclosporin A; Cyt.c, cytochrome c; DCFH-DA, 2′,7′-dichlorofluorescein diacetate; DPA, docosapentaenoic acid; EPA, eicosapentaenoic acid; HE, hydroethidine; JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazol carbocyanine iodide; MPT, membrane permeability transition; PUFA, polyunsaturated fatty acid; ROS, reactive oxygen species; and z-VAD-fmk, z-Val-Ala-Asp(OMe)-fluoromethylketone.

Kayo Arita, Hirotsugu Kobuchi, Toshihiko Utsumi et al. · Biochemical Pharmacology · 2001 · 119 citations

Life Sciences, Biochemistry, Cell Biology +17

The subcellular localization of aldehyde dehydrogenase in rat liver

Alan A. Horton, M C Barrett · Archives of Biochemistry and Biophysics · 1975 · 85 citations

Life Sciences, Biochemistry, Cell Biology +15

Caspase activation and cytochrome<i>c</i>release during HL-60 cell apoptosis induced by a nitric oxide donor

Munehisa Yabuki, Ken‐Ichiro Tsutsui, Alan A. Horton et al. · Free Radical Research · 2000 · 72 citations

Life Sciences, Cell Biology, Oncology +17

Resistance to nitric oxide-mediated apoptosis in HL-60 variant cells is associated with increased activities of Cu,Zn-superoxide dismutase and catalase

Munehisa Yabuki, Shinji Kariya, Rumi Ishisaka et al. · Free Radical Biology and Medicine · 1999 · 68 citations

Life Sciences, Biochemistry, Cell Biology +12

Inhibition of Stimulus-Specific Neutrophil Superoxide Generation by Alpha-Tocopherol

Tomoko Kanno, Toshihiko Utsumi, Hirotsugu Kobuchi et al. · Free Radical Research · 1995 · 51 citations

Life Sciences, Immunology, Pharmacology +13