Concepedia

Cardiolipin Externalization

Cardiolipin Externalization is a subcellular biochemical event characterized by the translocation of cardiolipin, a mitochondrial inner membrane phospholipid, to the outer mitochondrial membrane, where it serves as an early signaling platform for mitochondrial outer membrane permeabilization during intrinsic apoptosis.

21

Publications

2.6K

Citations

169

Authors

63

Institutions

Publications per year

2017–2026

6

Parents

Publications

21

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

Charleen T. Chu, Jing Ji, Ruben K. Dagda et al. · Nature Cell Biology · 2013 · 1K citations · Full text

, , +17

Phospholipid composition of highly purified mitochondrial outer membranes of rat liver and Neurospora crassa. Is cardiolipin present in the mitochondrial outer membrane?

Anton I.P.M. de Kroon, Danièle Dolis, Andreas Mayer et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1997 · 244 citations

, , +14

NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy

Valerian E. Kagan, Jianfei Jiang, Zhentai Huang et al. · Cell Death and Differentiation · 2016 · 241 citations · Full text

, , +12

Loss of Sam50 in hepatocytes induces cardiolipin‐dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury

Li Chen, Jun Dong, Siyang Liao et al. · Hepatology · 2022 · 123 citations

, , +17

Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury

Honglu Chao, Chao Lin, Qiang Zuo et al. · Journal of Neuroscience · 2019 · 119 citations · Full text

, , +17

1–5 of 21

Authors

169

  1. VE
    Valerian E. Kagan

    University of Pittsburgh, United States

    4 publications · 1.5K citations

    4

    h-index

  2. VA
    Vladimir A. Tyurin

    University of Pittsburgh, United States

    3 publications · 1.4K citations

    3

    h-index

  3. SC
    Simon C. Watkins

    University of Pittsburgh, United States

    3 publications · 1.4K citations

    3

    h-index

  4. YY
    Yulia Y. Tyurina

    University of Pittsburgh, United States

    3 publications · 1.4K citations

    3

    h-index

  5. ML
    Miriam L. Greenberg

    Wayne State University, United States

    2 publications · 312 citations

    2

    h-index

1–5 of 169

Institutions

63

  1. University of Pittsburgh

    Pittsburgh, United States

    4 h-index

    60 publications

    32.3K citations

  2. Utrecht University

    Utrecht, The Netherlands

    2 h-index

    9 publications

    1.4K citations

  3. Children's Hospital of Pittsburgh

    Pittsburgh, United States

    2 h-index

    2 publications

    1.2K citations

  4. VA Pittsburgh Healthcare System

    Pittsburgh, United States

    2 h-index

    2 publications

    320 citations

  5. Ludwig-Maximilians-Universität München

    Munich, Germany

    1 h-index

    2 publications

    488 citations

  6. Tumkur University

    Tumakuru, India

    1 h-index

    1 publications

    73 citations

  7. Czech Academy of Sciences, Institute of Microbiology

    Prague, Czechia

    1 h-index

    1 publications

    34 citations

  8. University of California San Diego

    San Diego, United States

    1 h-index

    2 publications

    40 citations

1–8 of 63

Venues

  1. 6

    h-index

  2. 2

    h-index

  3. Hepatology

    1 publications · 123 citations

    1

    h-index

  4. Nature Cell Biology

    NCB · 1 publications · 1K citations

    1

    h-index

  5. 1

    h-index

1–5