Concepedia

Card9-dependent Pathways

CARD9-Dependent Pathways is a signaling framework in innate immunity that transduces activation signals from C-type lectin receptors to downstream inflammatory responses through the adaptor protein CARD9, distinguishing it from other C-type lectin receptor-associated pathways by its specific reliance on CARD9 for NF-κB activation and antifungal defense.

78

Publications

10.2K

Citations

806

Authors

331

Institutions

Publications per year

2017–2026

35

Parents

Publications

78

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Bruno Lamas, Mathias L. Richard, Valentin Leducq et al. · Nature Medicine · 2016 · 1.4K citations · Full text

, , +16

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

Salomé LeibundGut‐Landmann, Olaf Groß, Matthew J. Robinson et al. · Nature Immunology · 2007 · 1.2K citations

, , +17

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

Andreas Gewies, Katrin Finger, Martin Jörg Schäfer et al. · Nature · 2006 · 848 citations

, , +14

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens

Yen-Michael S. Hsu, Yongliang Zhang, Yun You et al. · Nature Immunology · 2006 · 428 citations · Full text

, , +14

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors

Hiromitsu Hara, Chitose Ishihara, Arata Takeuchi et al. · Nature Immunology · 2007 · 361 citations

, , +13

1–5 of 78

Authors

806

  1. XL
    Xin Lin

    The University of Texas MD Anderson Cancer Center, United States

    11 publications · 1.7K citations

    11

    h-index

  2. JR
    Jürgen Ruland

    Technical University of Munich, Germany

    10 publications · 2.9K citations

    10

    h-index

  3. AP
    Anne Puel

    Inserm, France

    7 publications · 619 citations

    7

    h-index

  4. MM
    Mélanie Migaud

    Rockefeller University, United States

    6 publications · 593 citations

    6

    h-index

  5. HH
    Hiromitsu Hara

    Saga University, Japan

    6 publications · 611 citations

    6

    h-index

1–5 of 806

Institutions

331

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    10 h-index

    29 publications

    6.3K citations

  2. Technical University of Munich

    Munich, Germany

    10 h-index

    43 publications

    11.5K citations

  3. Inserm

    Paris, France

    9 h-index

    72 publications

    16.2K citations

  4. Université Paris Cité

    Paris, France

    8 h-index

    42 publications

    5.5K citations

  5. Institut des Maladies Génétiques Imagine

    Paris, France

    8 h-index

    33 publications

    3.9K citations

  6. TUM Klinikum

    Munich, Germany

    8 h-index

    37 publications

    7.7K citations

  7. Assistance Publique – Hôpitaux de Paris

    Paris, France

    7 h-index

    28 publications

    10.6K citations

  8. Harvard University

    Cambridge, United States

    7 h-index

    34 publications

    5.9K citations

1–8 of 331

Venues

  1. Nature Immunology

    6 publications · 2.4K citations

    6

    h-index

  2. Journal of Clinical Immunology

    5 publications · 198 citations

    5

    h-index

  3. The Journal of Immunology

    JI · 4 publications · 403 citations

    4

    h-index

  4. Journal of Cellular and Molecular Medicine

    4 publications · 77 citations

    4

    h-index

  5. Infection and Immunity

    IAI · 4 publications · 186 citations

    4

    h-index

1–5