Concepedia

Cap-dependent Rna Stability

Cap-Dependent RNA Stability is a molecular mechanism of mRNA longevity in which the 5' cap structure protects the transcript from exonucleolytic degradation and enhances translational efficiency, thereby distinguishing it from cap-independent modes of RNA stabilization that rely on alternative structural or sequence elements.

28

Publications

3.1K

Citations

136

Authors

46

Institutions

Publications per year

2017–2026

10

Parents

Publications

28

Reversible methylation of m6Am in the 5′ cap controls mRNA stability

Jan Mauer, Xiaobing Luo, Alexandre Blanjoie et al. · Nature · 2016 · 1.1K citations · Full text

, , +14

The major mRNA‐associated protein YB‐1 is a potent 5′ cap‐dependent mRNA stabilizer

Valentina Evdokimova, Peter Ruzanov, Hiroaki Imataka et al. · The EMBO Journal · 2001 · 278 citations · Full text

, , +16

5′ End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding

Xinfu Jiao, S.K. Doamekpor, Jeremy G. Bird et al. · Cell · 2017 · 238 citations · Full text

, , +10

A Mammalian Pre-mRNA 5′ End Capping Quality Control Mechanism and an Unexpected Link of Capping to Pre-mRNA Processing

Xinfu Jiao, Jeong Ho Chang, Turgay Kilic et al. · Molecular Cell · 2013 · 171 citations · Full text

, , +17

Capped mRNA Degradation Intermediates Accumulate in the Yeast <i>spb8-2</i> Mutant

Ronald Boeck, Bruno Lapeyre, Christine E. Brown et al. · Molecular and Cellular Biology · 1998 · 135 citations · Full text

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1–5 of 28

Authors

136

  1. MK
    Megerditch Kiledjian

    Rutgers, The State University of New Jersey, United States

    3 publications · 1.5K citations

    3

    h-index

  2. JJ
    Jacek Jemielity

    University of Warsaw, Poland

    3 publications · 73 citations

    3

    h-index

  3. JK
    Joanna Kowalska

    University of Warsaw, Poland

    3 publications · 73 citations

    3

    h-index

  4. XJ
    Xinfu Jiao

    Rutgers, The State University of New Jersey, United States

    3 publications · 1.5K citations

    3

    h-index

  5. LT
    Liang Tong

    Columbia University, United States

    2 publications · 409 citations

    2

    h-index

1–5 of 136

Institutions

46

  1. Rutgers, The State University of New Jersey

    New Brunswick, United States

    5 h-index

    15 publications

    5.1K citations

  2. New York University

    New York, United States

    3 h-index

    6 publications

    269 citations

  3. University of Warsaw

    Warsaw, Poland

    3 h-index

    22 publications

    534 citations

  4. Columbia University

    New York, United States

    3 h-index

    7 publications

    1.1K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    4 publications

    3.4K citations

  6. Heidelberg University

    Heidelberg, Germany

    2 h-index

    11 publications

    804 citations

  7. College of Europe, Warsaw

    Warsaw, Poland

    1 h-index

    2 publications

    42 citations

  8. Baylor College of Medicine

    Houston, United States

    1 h-index

    2 publications

    66 citations

1–8 of 46

Venues

  1. Molecular Cell

    4 publications · 420 citations

    4

    h-index

  2. Nucleic Acids Research

    3 publications · 142 citations

    3

    h-index

  3. RNA

    2 publications · 58 citations

    2

    h-index

  4. Cell

    2 publications · 366 citations

    2

    h-index

  5. Molecular and Cellular Biology

    MCB · 2 publications · 244 citations

    2

    h-index

1–5