Joanna Kowalska

Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo

Andreas N. Kuhn, Mustafa Diken, Sebastian Kreiter et al. · Gene Therapy · 2010 · 215 citations · Full text

Vaccination, Immature Dendritic Cells, Vaccine Development +11

Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells

Ewa Grudzien‐Nogalska, Jacek Jemielity, Joanna Kowalska et al. · RNA · 2007 · 148 citations · Full text

The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells

Pawel J. Sikorski, Marcin Warmiński, Dorota Kubacka et al. · Nucleic Acids Research · 2020 · 140 citations · Full text

Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS

Joanna Kowalska, Magdalena Lewdorowicz, Joanna Zuberek et al. · RNA · 2008 · 129 citations · Full text

Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation

Ryan W. Tibble, Anaïs Depaix, Joanna Kowalska et al. · Nature Chemical Biology · 2021 · 92 citations · Full text

Rna Structure Prediction, Molecular Biology, Enzyme Conformation +2