Concepedia

Candidate Compound Prioritization

Candidate Compound Prioritization is a computational or analytical method that ranks potential bioactive molecules according to their likelihood of favorable pharmacological properties and developability, thereby distinguishing itself from other drug-likeness assessment approaches by focusing explicitly on the sequential ordering of compounds to expedite the selection of optimal candidates for further experimental evaluation.

91

Publications

4.4K

Citations

513

Authors

202

Institutions

Publications per year

2017–2026

27

Parents

Publications

91

An Aggregation Advisor for Ligand Discovery

John J. Irwin, Da Duan, Hayarpi Torosyan et al. · Journal of Medicinal Chemistry · 2015 · 429 citations · Full text

, , +16

Natural Product-likeness Score and Its Application for Prioritization of Compound Libraries

Peter Ertl, Silvio Roggo, Ansgar Schuffenhauer · Journal of Chemical Information and Modeling · 2007 · 413 citations

, , +17

Overview on the Rule of Five

Michael P. Pollastri · Current Protocols in Pharmacology · 2010 · 237 citations

, , +16

The Knowledge-Gradient Algorithm for Sequencing Experiments in Drug Discovery

Diana M. Negoescu, Peter I. Frazier, Warren B. Powell · INFORMS journal on computing · 2010 · 142 citations

, , +11

Drug-like Index:  A New Approach To Measure Drug-like Compounds and Their Diversity

Jun Xu, James Stevenson · Journal of Chemical Information and Computer Sciences · 2000 · 135 citations

, , +14

1–5 of 91

Authors

513

  1. JB
    Jürgen Bajorath

    University of Bonn, Germany

    7 publications · 202 citations

    7

    h-index

  2. NT
    N. Thirupathi Rao

    Osmania University, India

    4 publications · 58 citations

    4

    h-index

  3. YH
    Ye Hu

    University of Bonn, Germany

    4 publications · 148 citations

    4

    h-index

  4. SS
    Spencer S. Ericksen

    University of Wisconsin–Madison, United States

    3 publications · 103 citations

    3

    h-index

  5. SA
    Scott A. Wildman

    University of Wisconsin–Madison, United States

    3 publications · 103 citations

    3

    h-index

1–5 of 513

Institutions

202

  1. University of Bonn

    Bonn, Germany

    5 h-index

    13 publications

    426 citations

  2. Novartis (Switzerland)

    Basel, Switzerland

    5 h-index

    17 publications

    1.5K citations

  3. Osmania University

    Hyderabad, India

    4 h-index

    9 publications

    132 citations

  4. Pfizer (United States)

    New York, United States

    3 h-index

    29 publications

    2.9K citations

  5. University of Washington

    Seattle, United States

    3 h-index

    16 publications

    361 citations

  6. Morgridge Institute for Research

    Madison, United States

    3 h-index

    7 publications

    287 citations

  7. Novartis Institutes for BioMedical Research

    Basel, Switzerland

    3 h-index

    8 publications

    1.4K citations

  8. University of Wisconsin–Madison

    Madison, United States

    3 h-index

    22 publications

    662 citations

1–8 of 202

Venues

  1. Journal of Chemical Information and Modeling

    JCIM · 11 publications · 865 citations

    10

    h-index

  2. Journal of Medicinal Chemistry

    7 publications · 719 citations

    7

    h-index

  3. 4

    h-index

  4. 4

    h-index

  5. Journal of Molecular Graphics and Modelling

    3 publications · 46 citations

    3

    h-index

1–5