Da Duan

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.

James G. Herman, Farida Latif, Y Weng et al. · Proceedings of the National Academy of Sciences · 1994 · 1.5K citations · Full text

Epigenetic Change, Dna Methylation, Pathology +16

Structure-based discovery of opioid analgesics with reduced side effects

Aashish Manglik, Henry J. Lin, Dipendra K. Aryal et al. · Nature · 2016 · 925 citations · Full text

Health Sciences, Pain Medicine, Structure-based Discovery +8

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Mark A. Huffman, Anna Fryszkowska, Oscar Alvizo et al. · Science · 2019 · 601 citations

Enzyme-catalyzed Reactions, Biomanufacturing, Biosynthesis +15

An Aggregation Advisor for Ligand Discovery

John J. Irwin, Da Duan, Hayarpi Torosyan et al. · Journal of Medicinal Chemistry · 2015 · 423 citations · Full text

Pharmaceutical Research, Hit Identification, Chemistry +22

Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612

Lite Ge, Chengfeng Xun, Wenshui Li et al. · Journal of Nanobiotechnology · 2021 · 168 citations · Full text