Concepedia

Bridge Helix

The Bridge Helix is a conserved α-helical structural domain within RNA polymerase that functions as a dynamic scaffold facilitating nucleotide addition by modulating conformational changes during transcriptional elongation.

41

Publications

2.4K

Citations

236

Authors

116

Institutions

Publications per year

2017–2026

13

Parents

Publications

41

JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications

Vignesh Kasinath, Curtis Beck, Paul Sauer et al. · Science · 2021 · 259 citations · Full text

, , +17

Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation

Steven Tuske, Stefan G. Sarafianos, Xinyue Wang et al. · Cell · 2005 · 199 citations · Full text

, , +10

Millisecond dynamics of RNA polymerase II translocation at atomic resolution

Daniel‐Adriano Silva, Dahlia R. Weiss, Fátima Pardo Avila et al. · Proceedings of the National Academy of Sciences · 2014 · 157 citations

, , +17

Allosteric control of <i>Escherichia coli</i> rRNA promoter complexes by DksA

Steven T. Rutherford, Courtney L. Villers, Jeong‐Hyun Lee et al. · Genes & Development · 2009 · 141 citations · Full text

, , +17

A New Class of Bacterial RNA Polymerase Inhibitor Affects Nucleotide Addition

Irina Artsimovitch, Clement Chu, A. Simon Lynch et al. · Science · 2003 · 101 citations

, , +17

1–5 of 41

Authors

236

  1. ZF
    Zachary F. Burton

    Michigan State University, United States

    5 publications · 159 citations

    5

    h-index

  2. IA
    Irina Artsimovitch

    The Ohio State University, United States

    4 publications · 231 citations

    4

    h-index

  3. RO
    Robert O. J. Weinzierl

    Imperial College London, United Kingdom

    4 publications · 203 citations

    4

    h-index

  4. ML
    Maria L. Kireeva

    Frederick National Laboratory for Cancer Research, United States

    4 publications · 154 citations

    4

    h-index

  5. RI
    Robert I. Cukier

    Michigan State University, United States

    4 publications · 133 citations

    4

    h-index

1–5 of 236

Institutions

116

  1. Imperial College London

    London, United Kingdom

    5 h-index

    15 publications

    751 citations

  2. Michigan State University

    East Lansing, United States

    5 h-index

    26 publications

    789 citations

  3. The Ohio State University

    Columbus, United States

    4 h-index

    5 publications

    182 citations

  4. Rutgers, The State University of New Jersey

    New Brunswick, United States

    4 h-index

    30 publications

    3.9K citations

  5. University of Wisconsin–Madison

    Madison, United States

    4 h-index

    16 publications

    1.6K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    9 publications

    1.8K citations

  7. University of Oklahoma

    Norman, United States

    3 h-index

    12 publications

    437 citations

  8. University of California San Diego

    San Diego, United States

    3 h-index

    4 publications

    314 citations

1–8 of 116

Venues

  1. Nature Communications

    4 publications · 237 citations

    4

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 280 citations

    4

    h-index

  3. Nucleic Acids Research

    4 publications · 122 citations

    4

    h-index

  4. PLoS Genetics

    3 publications · 91 citations

    3

    h-index

  5. Journal of Biological Chemistry

    JBC · 3 publications · 128 citations

    3

    h-index

1–5