Daniel‐Adriano Silva

De novo design of potent and selective mimics of IL-2 and IL-15

Daniel‐Adriano Silva, Shawn Yu, Umut Y. Ulge et al. · Nature · 2019 · 524 citations · Full text

Cytokine, Medicine, Selective Mimics +6

Massively parallel de novo protein design for targeted therapeutics

Aaron Chevalier, Daniel‐Adriano Silva, Derrick R. Hicks et al. · Nature · 2017 · 477 citations · Full text

Natural Sciences, Computational Biology, Structure-based Drug Design +8

Monitoring and Inhibition of Insulin Fibrillation by a Small Organic Fluorogen with Aggregation-Induced Emission Characteristics

Yuning Hong, Luming Meng, Sijie Chen et al. · Journal of the American Chemical Society · 2011 · 389 citations

Amyloidosis Kinetics, Protein Assembly, Insulin Fibrillation +21

A Role for Both Conformational Selection and Induced Fit in Ligand Binding by the LAO Protein

Daniel‐Adriano Silva, Gregory R. Bowman, Alejandro Sosa‐Peinado et al. · PLoS Computational Biology · 2011 · 235 citations · Full text

Engineering, Protein Assembly, Molecular Biology +20

Comprehensive computational design of ordered peptide macrocycles

Parisa Hosseinzadeh, Gaurav Bhardwaj, Vikram Khipple Mulligan et al. · Science · 2017 · 216 citations · Full text