Concepedia

Branch Point Sequence

Branch Point Sequence is a conserved nucleotide sequence within the intron of a pre-mRNA transcript that serves as the site for the initial 2'-OH attack during RNA splicing, distinguishing it by its essential role in lariat formation through a specific adenosine residue located upstream of the 3' splice site.

240

Publications

17.2K

Citations

800

Authors

298

Institutions

Publications per year

2017–2026

27

Parents

Publications

240

[16] Splice junctions, branch point sites, and exons: Sequence statistics, identification, and applications to genome project

Periannan Senapathy, Marvin B. Shapiro, Nomi L. Harris · Methods in enzymology on CD-ROM/Methods in enzymology · 1990 · 686 citations

, , +14

Lariat RNA's as Intermediates and Products in the Splicing of Messenger RNA precursors

Richard A. Padgett, Maria M. Konarska, Paula J. Grabowski et al. · Science · 1984 · 482 citations

, , +15

Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point

Rachel Darman, Michael Seiler, Anant A. Agrawal et al. · Cell Reports · 2015 · 463 citations · Full text

, , +14

A catalogue of splice junction and putative branch point sequences from plant introns

John W. Brown · Nucleic Acids Research · 1986 · 374 citations · Full text

, , +16

The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC

J. Andrew Berglund, Katrin F. Chua, Nadja Abovich et al. · Cell · 1997 · 343 citations · Full text

, , +9

1–5 of 240

Authors

800

  1. MR
    Michael Rosbash

    Brandeis University, United States

    9 publications · 823 citations

    9

    h-index

  2. JA
    J. Andrew Berglund

    University of Oregon, United States

    8 publications · 661 citations

    8

    h-index

  3. CW
    Christopher W. J. Smith

    University of Cambridge, United Kingdom

    6 publications · 855 citations

    6

    h-index

  4. RR
    Robin Reed

    Harvard University, United States

    5 publications · 842 citations

    5

    h-index

  5. YS
    Yigong Shi

    Tsinghua University, China

    4 publications · 592 citations

    4

    h-index

1–5 of 800

Institutions

298

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    26 publications

    4K citations

  2. Harvard University

    Cambridge, United States

    9 h-index

    22 publications

    3.7K citations

  3. Brandeis University

    Waltham, United States

    8 h-index

    16 publications

    1.6K citations

  4. University of Wisconsin–Madison

    Madison, United States

    6 h-index

    15 publications

    1.1K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    17 publications

    777 citations

  6. University of California, San Francisco

    San Francisco, United States

    5 h-index

    18 publications

    1.2K citations

  7. Columbia University

    New York, United States

    5 h-index

    13 publications

    758 citations

  8. Max Planck Institute for Biophysical Chemistry

    Göttingen, Germany

    5 h-index

    16 publications

    890 citations

1–8 of 298

Venues

  1. Molecular and Cellular Biology

    MCB · 38 publications · 2K citations

    29

    h-index

  2. Nucleic Acids Research

    30 publications · 2K citations

    22

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  3. RNA

    18 publications · 618 citations

    15

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  4. Journal of Biological Chemistry

    JBC · 14 publications · 787 citations

    14

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 900 citations

    12

    h-index

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