Concepedia

Biopharmaceutical Downstream Processing

Biopharmaceutical Downstream Processing is a singular academic concept referring to the series of purification and isolation techniques applied after biological production to separate, refine, and formulate biopharmaceuticals from complex mixtures, distinguished from upstream processes by its focus on product recovery and quality assurance through physical, chemical, and biochemical separation methods.

132

Publications

5.2K

Citations

573

Authors

161

Institutions

Publications per year

2017–2026

61

Parents

Publications

132

Process analytical technology (PAT) for biopharmaceutical products: Part I. concepts and applications

E.K. Read, J.T. Park, Rakhi B. Shah et al. · Biotechnology and Bioengineering · 2009 · 216 citations

, , +17

Process analytical technology (PAT) for biopharmaceutical products: Part II. Concepts and applications

E.K. Read, Rakhi B. Shah, B.S. Riley et al. · Biotechnology and Bioengineering · 2009 · 198 citations

, , +17

Aggregation Stability of a Monoclonal Antibody During Downstream Processing

Paolo Arosio, Giuliano Barolo, Thomas Müller‐Späth et al. · Pharmaceutical Research · 2011 · 119 citations · Full text

, , +16

Expression of difficult‐to‐remove host cell protein impurities during extended Chinese hamster ovary cell culture and their impact on continuous bioprocessing

Kristin N. Valente, Abraham M. Lenhoff, Kelvin H. Lee · Biotechnology and Bioengineering · 2014 · 103 citations

, , +17

Applied advanced process analytics in biopharmaceutical manufacturing: Challenges and prospects in real-time monitoring and control

Cenk Ündey, Sinem Ertunç, Thomas Mistretta et al. · Journal of Process Control · 2010 · 99 citations

, , +16

1–5 of 132

Authors

573

  1. JH
    Jürgen Hubbuch

    Karlsruhe Institute of Technology, Germany

    7 publications · 240 citations

    7

    h-index

  2. AS
    Anurag S. Rathore

    Indian Institute of Technology Delhi, India

    6 publications · 639 citations

    6

    h-index

  3. JS
    Jochen Strube

    Clausthal University of Technology, Germany

    5 publications · 133 citations

    5

    h-index

  4. JF
    Johannes F. Buyel

    Fraunhofer Institute for Molecular Biology and Applied Ecology, Germany

    5 publications · 195 citations

    5

    h-index

  5. MO
    Marcel Ottens

    Delft University of Technology, Netherlands

    5 publications · 220 citations

    5

    h-index

1–5 of 573

Institutions

161

  1. Indian Institute of Technology Delhi

    New Delhi, India

    6 h-index

    18 publications

    1.3K citations

  2. Karlsruhe Institute of Technology

    Karlsruhe, Germany

    6 h-index

    19 publications

    680 citations

  3. University College London

    London, United Kingdom

    6 h-index

    19 publications

    637 citations

  4. RWTH Aachen University

    Aachen, Germany

    5 h-index

    9 publications

    337 citations

  5. Fraunhofer Institute for Molecular Biology and Applied Ecology

    Schmallenberg, Germany

    5 h-index

    11 publications

    300 citations

  6. Delft University of Technology

    Delft, The Netherlands

    5 h-index

    11 publications

    448 citations

  7. Clausthal University of Technology

    Clausthal-Zellerfeld, Germany

    4 h-index

    10 publications

    336 citations

  8. Boehringer Ingelheim (Germany)

    Ingelheim, Germany

    4 h-index

    26 publications

    583 citations

1–8 of 161

Venues

  1. Biotechnology Progress

    19 publications · 554 citations

    17

    h-index

  2. Biotechnology and Bioengineering

    17 publications · 1.1K citations

    16

    h-index

  3. Journal of Chromatography A

    8 publications · 272 citations

    8

    h-index

  4. Biotechnology Journal

    6 publications · 365 citations

    6

    h-index

  5. Journal of Chemical Technology & Biotechnology

    5 publications · 170 citations

    5

    h-index

1–5