Concepedia

Thomas Müller‐Späth

TM

30

Publications

1.5K

Citations

21

H-Index

2003

Active since

Affiliations

ETH Zurich(Current)

Bioengineering (Switzerland)

Institute for Biomedical Engineering

Bristol-Myers Squibb (United States)

Merck Serono (Switzerland)

Thomas Müller‐Späth is an author at ETH Zurich specializing in engineering, chromatography, and medicine.

Top concepts

MedicineChromatographyEngineeringBioanalysisAnalytical ChemistryBiomolecular EngineeringBiotechnologyBiochemistryDrug AnalysisAntibody Engineering

Publications per year

2003–2022

30

Publications

30

Twin-column CaptureSMB: A novel cyclic process for protein A affinity chromatography

Monica Angarita, Thomas Müller‐Späth, Daniel Baur et al. · Journal of Chromatography A · 2015 · 159 citations

Protein Chemistry, Affinity Chromatography, Biochemistry +6

Comparison of batch and continuous multi‐column protein A capture processes by optimal design

Daniel Baur, Monica Angarita, Thomas Müller‐Späth et al. · Biotechnology Journal · 2016 · 137 citations · Full text

Engineering, Analytical Ultracentrifugation, Protein Purification +21

Chromatographic separation of three monoclonal antibody variants using multicolumn countercurrent solvent gradient purification (MCSGP)

Thomas Müller‐Späth, Lars Aumann, Lena Melter et al. · Biotechnology and Bioengineering · 2008 · 129 citations

Engineering, Solvent Gradients, Immunology +20

Aggregation Stability of a Monoclonal Antibody During Downstream Processing

Paolo Arosio, Giuliano Barolo, Thomas Müller‐Späth et al. · Pharmaceutical Research · 2011 · 117 citations · Full text

Immunocytochemical Technique, Bioanalysis, Immunology +7

Optimal model‐based design of the twin‐column CaptureSMB process improves capacity utilization and productivity in protein A affinity capture

Daniel Baur, Monica Angarita, Thomas Müller‐Späth et al. · Biotechnology Journal · 2015 · 105 citations

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