Concepedia
Statistics
Publications
30
Citations
1.5K
H-Index
21
Active since
2003
Affiliations
ETH Zurich(Current)
Bioengineering (Switzerland)
Institute for Biomedical Engineering
Bristol-Myers Squibb (United States)
Merck Serono (Switzerland)
Thomas Müller‐Späth is an author at ETH Zurich specializing in engineering, chromatography, and medicine.
Top concepts
MedicineChromatographyEngineeringBioanalysisAnalytical ChemistryBiomolecular EngineeringBiotechnologyBiochemistryDrug AnalysisAntibody Engineering
Publications per year
2003–2022
Twin-column CaptureSMB: A novel cyclic process for protein A affinity chromatography
Monica Angarita, Thomas Müller‐Späth, Daniel Baur et al. · Journal of Chromatography A · 2015 · 159 citations
Protein Chemistry, Affinity Chromatography, Biochemistry +6
Comparison of batch and continuous multi‐column protein A capture processes by optimal design
Daniel Baur, Monica Angarita, Thomas Müller‐Späth et al. · Biotechnology Journal · 2016 · 137 citations · Full text
Engineering, Analytical Ultracentrifugation, Protein Purification +21
Chromatographic separation of three monoclonal antibody variants using multicolumn countercurrent solvent gradient purification (MCSGP)
Thomas Müller‐Späth, Lars Aumann, Lena Melter et al. · Biotechnology and Bioengineering · 2008 · 129 citations
Engineering, Solvent Gradients, Immunology +20
Aggregation Stability of a Monoclonal Antibody During Downstream Processing
Paolo Arosio, Giuliano Barolo, Thomas Müller‐Späth et al. · Pharmaceutical Research · 2011 · 117 citations · Full text
Immunocytochemical Technique, Bioanalysis, Immunology +7
Optimal model‐based design of the twin‐column CaptureSMB process improves capacity utilization and productivity in protein A affinity capture
Daniel Baur, Monica Angarita, Thomas Müller‐Späth et al. · Biotechnology Journal · 2015 · 105 citations
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