Binding Site Conservation is a methodological principle in antibody humanization that preserves the non-human complementarity-determining regions responsible for antigen recognition while grafting them into a human antibody framework to maintain binding affinity and specificity.
63
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3.6K
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377
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168
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Publications per year
2017–2026
13
Parents
Publications
63
microRNA target prediction programs predict many false positives
Natalia Pinzón, Blaise Li, Laura Martínez Gómez et al. · Genome Research · 2016 · 277 citations · Full text
A Specific Amino Acid Binding Site Composed of RNA
Michael Yarus · Science · 1988 · 205 citations
Christopher B. Phelps, Ruiqi Rachel Wang, Shelly S. Choo et al. · Journal of Biological Chemistry · 2009 · 196 citations · Full text
1–5 of 63
Authors
377
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2
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2
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- BK
2
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2
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2
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1–5 of 377
Institutions
168
National Institutes of Health
Bethesda, United States
4 h-index
27 publications
1.5K citations
University of Oxford
Oxford, United Kingdom
3 h-index
6 publications
581 citations
Harvard University
Cambridge, United States
3 h-index
6 publications
1K citations
University of Edinburgh
Edinburgh, United Kingdom
3 h-index
11 publications
521 citations
Aarhus University
Aarhus, Denmark
2 h-index
7 publications
192 citations
Consejo Nacional de Investigaciones Científicas y Técnicas
Buenos Aires, Argentina
2 h-index
9 publications
256 citations
Baylor College of Medicine
Houston, United States
2 h-index
8 publications
412 citations
Gdańsk University of Technology
Gdansk, Poland
2 h-index
2 publications
113 citations
1–8 of 168
Venues
- PLoS ONE
5 publications · 204 citations
5
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- Proceedings of the National Academy of Sciences
PNAS · 4 publications · 332 citations
4
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- Journal of Biological Chemistry
JBC · 4 publications · 281 citations
4
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- Molecular and Cellular Biology
MCB · 3 publications · 147 citations
3
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- Biochemistry
3 publications · 173 citations
3
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1–5