Concepedia

Bfl-1 Function

Bfl-1 Function is a molecular biological concept referring to the anti-apoptotic activity mediated by the Bcl-2 homology domain-containing protein Bfl-1, which selectively inhibits mitochondrial outer membrane permeabilization and subsequent caspase activation in response to cellular stress signals.

66

Publications

4.5K

Citations

397

Authors

157

Institutions

Publications per year

2017–2026

8

Variants

Bfl1 Function

Parents

Publications

66

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappa B that blocks TNFalpha -induced apoptosis

W.-X. Zong, Leonard C. Edelstein, Chi Chen et al. · Genes & Development · 1999 · 727 citations · Full text

, , +17

4-1BB Promotes the Survival of CD8+ T Lymphocytes by Increasing Expression of Bcl-xL and Bfl-1

Hyeon‐Woo Lee, Su-Jung Park, Beom K. Choi et al. · The Journal of Immunology · 2002 · 365 citations · Full text

, , +14

Bcl-2 Family Member Bfl-1/A1 Sequesters Truncated Bid to Inhibit Its Collaboration with Pro-apoptotic Bak or Bax

Arlette B. Werner, Evert de Vries, Stephen W. G. Tait et al. · Journal of Biological Chemistry · 2002 · 158 citations · Full text

, , +17

Differential Regulation of Bax and Bak by Anti-apoptotic Bcl-2 Family Proteins Bcl-B and Mcl-1

Dayong Zhai, Chaofang Jin, Ziwei Huang et al. · Journal of Biological Chemistry · 2008 · 138 citations · Full text

, , +17

Mcl-1 and Bcl-xL Cooperatively Maintain Integrity of Hepatocytes in Developing and Adult Murine Liver†

Hayato Hikita, Tetsuo Takehara, Satoshi Shimizu et al. · Hepatology · 2009 · 127 citations · Full text

, , +13

1–5 of 66

Authors

397

  1. NB
    Nathalie Bonnefoy

    Inserm, France

    8 publications · 248 citations

    8

    h-index

  2. JK
    Jae‐Kyun Ko

    Johnson University, United States

    6 publications · 163 citations

    6

    h-index

  3. CG
    Céline Gélinas

    McGill University, Canada

    5 publications · 924 citations

    5

    h-index

  4. MJ
    Matthew J. Simmons

    Johnson University, United States

    4 publications · 197 citations

    4

    h-index

  5. CW
    Chul Woo Kim

    Seoul National University, South Korea

    4 publications · 101 citations

    4

    h-index

1–5 of 397

Institutions

157

  1. Johnson University

    Knoxville, United States

    9 h-index

    26 publications

    1.8K citations

  2. Inserm

    Paris, France

    9 h-index

    44 publications

    1.3K citations

  3. Seoul National University Hospital

    Seoul, South Korea

    6 h-index

    29 publications

    663 citations

  4. Université Claude Bernard Lyon 1

    Villeurbanne, France

    6 h-index

    29 publications

    728 citations

  5. Rutgers, The State University of New Jersey

    New Brunswick, United States

    5 h-index

    11 publications

    3.9K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    4 h-index

    22 publications

    978 citations

  7. Rutgers Cancer Institute

    New Brunswick, United States

    3 h-index

    5 publications

    270 citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    11 publications

    240 citations

1–8 of 157

Venues

  1. Journal of Biological Chemistry

    JBC · 7 publications · 553 citations

    7

    h-index

  2. Oncogene

    6 publications · 418 citations

    6

    h-index

  3. Cell Death and Differentiation

    CDD · 4 publications · 221 citations

    4

    h-index

  4. PubMed

    Repository · 4 publications · 181 citations

    4

    h-index

  5. Blood

    3 publications · 189 citations

    3

    h-index

1–5